Role of Complement in Multiorgan Failure
Joint Authors
Rittirsch, Daniel
Redl, Heinz
Huber-Lang, Markus S.
Source
Journal of Immunology Research
Issue
Vol. 2012, Issue 2012 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-20
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Multiorgan failure (MOF) represents the leading cause of death in patients with sepsis and systemic inflammatory response syndrome (SIRS) following severe trauma.
The underlying immune response is highly complex and involves activation of the complement system as a crucial entity of innate immunity.
Uncontrolled activation of the complement system during sepsis and SIRS with in excessive generation of complement activation products contributes to an ensuing dysfunction of various organ systems.
In the present review, mechanisms of the inflammatory response in the development of MOF in sepsis and SIRS with particular focus on the complement system are discussed.
American Psychological Association (APA)
Rittirsch, Daniel& Redl, Heinz& Huber-Lang, Markus S.. 2012. Role of Complement in Multiorgan Failure. Journal of Immunology Research،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-996975
Modern Language Association (MLA)
Rittirsch, Daniel…[et al.]. Role of Complement in Multiorgan Failure. Journal of Immunology Research Vol. 2012, no. 2012 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-996975
American Medical Association (AMA)
Rittirsch, Daniel& Redl, Heinz& Huber-Lang, Markus S.. Role of Complement in Multiorgan Failure. Journal of Immunology Research. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-996975
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-996975