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Semiconductor Quantum Dots Surface Modification for Potential Cancer Diagnostic and Therapeutic Applications
Joint Authors
Wang, Jidong
Han, Shumin
Ke, Dandan
Wang, Ruibing
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-23
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Semiconductor Quantum dots (QDs) have generated extensive interest for biological and clinical applications.
These applications arise from their unique properties, such as high brightness, long-term stability, simultaneous detection of multiple signals, tunable emission spectra.
However, high-quality QDs, whether single or core-shell QDs, are most commonly synthesized in organic solution and surface-stabilized with hydrophobic organic ligands and thus lack intrinsic aqueous solubility.
For biological applications, very often it is necessary to make the QDs dispersible in water and therefore to modify the QD surfaces with various bifunctional surface ligands or caps to promote solubility in aqueous media.
Well-defined methods have been developed for QD surface modification to impart biocompatibility to these systems.
In this review, we summarize the recent progress and strategies of QDs surface modification for potential cancer diagnostic and therapeutic applications.
In addition, the question that arose from QD surface modification, such as impact of size increase of QD bioconjugates after surface-functionalization or surface modification on photophysical properties of QDs, are also discussed.
American Psychological Association (APA)
Wang, Jidong& Han, Shumin& Ke, Dandan& Wang, Ruibing. 2012. Semiconductor Quantum Dots Surface Modification for Potential Cancer Diagnostic and Therapeutic Applications. Journal of Nanomaterials،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-997214
Modern Language Association (MLA)
Wang, Jidong…[et al.]. Semiconductor Quantum Dots Surface Modification for Potential Cancer Diagnostic and Therapeutic Applications. Journal of Nanomaterials No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-997214
American Medical Association (AMA)
Wang, Jidong& Han, Shumin& Ke, Dandan& Wang, Ruibing. Semiconductor Quantum Dots Surface Modification for Potential Cancer Diagnostic and Therapeutic Applications. Journal of Nanomaterials. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-997214
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-997214