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Some hematological and biochemical alterations consequent to concurrent administration of ivermectin and rafoxanide in rams
Other Title(s)
بعض التغيرات الدمويه والبيوكيميائيه الناتجة عن الاستخدام المتزامن للأيفرميكتين والرافوكسانيد في الكباش
Parallel Title
بعض التغيرات الدمويه والبيوكيميائيه الناتجة عن الاستخدام المتزامن للأيفرميكتين والرافوكسانيد في الكباش
Joint Authors
al-Jazzar, Usamah Bahjat
al-Ghoneimy, Ashraf A.
Source
Kafr El-Sheikh Veterinary Medical Journal
Issue
Vol. 5, Issue 2 (30 Oct. 2007), pp.154-172, 19 p.
Publisher
Kafr El-Sheikh University Faculty of Veterinary Medicine
Publication Date
2007-10-30
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Topics
Abstract EN
Ivermectin and Rafoxanide are widely used in sheep as endoectoparasiticidal and fasciolicidal drugs.
The effects of ivermectin and rafoxanide as well as their concurrent use as prophylactic drugs on hematological and serum biochemical parameters were studied in 20 apparently clinically healthy rams, classified into 4 equal groups .
The 1st group was left without treatment (control).
The 2nd group was injected s/c with ivermectin (0.2 mg kg-1).
The 3rd group was injected s/c with rafoxanide (3 mg kg-1).
While, the 4th group was injected s/c with both drugs (0.2 mg ivermectin and 3 mg rafoxanide kg-1).
Blood samples were collected weekly for 2 weeks for hematological and biochemical studies.
The obtained results with ivermectin treated group revealed, a significant decrease in erythrocytic count, PCV % and Hb concentration,MCV and MCHC% .
Meanwhile, significant increase in serum AST and ALT activities was recorded.
The rafoxanide treated group provoked a significant decrease in leuckocytic and erythrocytic counts, Hb%, PCV%, MCV, MCH and MCHC% as well as serum triglycerides level.
Mean while, a significant increase in serum cholesterol and LDL-c levels was reported.Moreover, the group treated S/C with both drugs, elicited a significant decrease in erythrocytic and leukocytic counts, PCV%, MCV, MCH, MCHC%, triglyceride levels and Hb%.
American Psychological Association (APA)
al-Ghoneimy, Ashraf A.& al-Jazzar, Usamah Bahjat. 2007. Some hematological and biochemical alterations consequent to concurrent administration of ivermectin and rafoxanide in rams. Kafr El-Sheikh Veterinary Medical Journal،Vol. 5, no. 2, pp.154-172.
https://search.emarefa.net/detail/BIM-99740
Modern Language Association (MLA)
al-Ghoneimy, Ashraf A.& al-Jazzar, Usamah Bahjat. Some hematological and biochemical alterations consequent to concurrent administration of ivermectin and rafoxanide in rams. Kafr El-Sheikh Veterinary Medical Journal Vol. 5, no. 2 (2007), pp.154-172.
https://search.emarefa.net/detail/BIM-99740
American Medical Association (AMA)
al-Ghoneimy, Ashraf A.& al-Jazzar, Usamah Bahjat. Some hematological and biochemical alterations consequent to concurrent administration of ivermectin and rafoxanide in rams. Kafr El-Sheikh Veterinary Medical Journal. 2007. Vol. 5, no. 2, pp.154-172.
https://search.emarefa.net/detail/BIM-99740
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 168-173
Record ID
BIM-99740