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On Stabilization of PVPAPVA Electrospun Nanofiber Membrane and Its Effect on Material Properties and Biocompatibility
Joint Authors
Franco, Rose Ann
Min, Young-Ki
Yang, Hun-Mo
Lee, Byong-Taek
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-21
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
A novel nanofiber membrane was fabricated by electrospinning composed of polyvinyl phosphonic acid (PVPA) and polyvinyl alcohol (PVA).
Stabilization was done due to the high dissolvability of the membrane when in contact with water.
Physical treatment was done by exposure to heat at 150°C in a vacuum environment at different periods of time.
Chemical crosslinking was done by immersion in methanol and methanol/ glutaraldehyde.
A heat-exposed membrane was also further crosslinked chemically.
All conditions were compared with regards to its effect on the material properties of the membranes and its biological response in vitro with MG-63 osteoblast-like cell line.
Visual examination and dimensional analyses showed that heat treatment produced discoloration on the membrane surface and chemical crosslinking reduced membrane dimensions.
Tensile strength and strain improved in crosslinked membranes compared to noncrosslinked counterpart.
Swelling and degradation was also investigated and was seen to vary depending on the crosslinking condition.
Biocompatibility was observed to be more favorable in heat-treated membranes.
American Psychological Association (APA)
Franco, Rose Ann& Min, Young-Ki& Yang, Hun-Mo& Lee, Byong-Taek. 2012. On Stabilization of PVPAPVA Electrospun Nanofiber Membrane and Its Effect on Material Properties and Biocompatibility. Journal of Nanomaterials،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-997632
Modern Language Association (MLA)
Franco, Rose Ann…[et al.]. On Stabilization of PVPAPVA Electrospun Nanofiber Membrane and Its Effect on Material Properties and Biocompatibility. Journal of Nanomaterials No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-997632
American Medical Association (AMA)
Franco, Rose Ann& Min, Young-Ki& Yang, Hun-Mo& Lee, Byong-Taek. On Stabilization of PVPAPVA Electrospun Nanofiber Membrane and Its Effect on Material Properties and Biocompatibility. Journal of Nanomaterials. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-997632
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-997632