In Vitro Cytotoxicity Assay on Gold Nanoparticles with Different Stabilizing Agents
Joint Authors
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-04
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Noble gold nanoparticles (AuNps) are generally nontoxic due to their inert nature.
The gold nanoparticles are easily tagged with various proteins and biomolecules rich in aminoacid leading to important biomedical applications including targeted drug delivery, cellular imaging, and biosensing.
In this study, three cytotoxicity detection assays 3-(4,5-dimethylthiozol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT), neutral red cell, and lactate dehydrogenase (LDH) on gold nanoparticles stabilized with citrate, starch, and gum arabic are used.
The assays used are based on different mode of detection like LDH release, MTT metabolism, and neutral red uptake.
We found that the AuNps stabilized with citrate are very sensitive to the change of concentration and time assay compared to starch and gum arabic stabilized gold nanoparticles.
American Psychological Association (APA)
Vijayakumar, S.& Ganesan, S.. 2012. In Vitro Cytotoxicity Assay on Gold Nanoparticles with Different Stabilizing Agents. Journal of Nanomaterials،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-998394
Modern Language Association (MLA)
Vijayakumar, S.& Ganesan, S.. In Vitro Cytotoxicity Assay on Gold Nanoparticles with Different Stabilizing Agents. Journal of Nanomaterials No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-998394
American Medical Association (AMA)
Vijayakumar, S.& Ganesan, S.. In Vitro Cytotoxicity Assay on Gold Nanoparticles with Different Stabilizing Agents. Journal of Nanomaterials. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-998394
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-998394