Determination of Collagen Fibers Arrangement in Bone Tissue by Using Transformations of Raman Spectra Maps
Joint Authors
Buchwald, Tomasz
Kozielski, Marek
Szybowicz, Mirosław
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-28
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The goal of this work was to evaluate the ability of Raman spectroscopy to identify molecular organization and chemical composition of extracellular matrix such as the collagen fibers arrangement, the level of mineralization, and the carbonate accumulation in mineral phase in spongy bone of the human head of the femur.
Changes in composition and structure of the spongy bone tissue were illustrated using maps of polarized Raman spectra.
In particular, the purpose of the present study was determination of arrangement of mineralized collagen on surface of trabecula by using transformations of Raman spectra maps.
Transformations of Raman spectra maps were needed in order to remove impact of chemical composition on images of Raman spectra map, which display the collagen fibers orientation.
These transformations allow to obtain simultaneously the distribution of constituents of bone and arrangement of collagen fibers on tissue surface.
A method to indicate the collagen orientations is developed to understand the molecular organization in healthy and unhealthy bone at the microstructural level.
American Psychological Association (APA)
Buchwald, Tomasz& Kozielski, Marek& Szybowicz, Mirosław. 2012. Determination of Collagen Fibers Arrangement in Bone Tissue by Using Transformations of Raman Spectra Maps. Journal of Spectroscopy،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-998743
Modern Language Association (MLA)
Buchwald, Tomasz…[et al.]. Determination of Collagen Fibers Arrangement in Bone Tissue by Using Transformations of Raman Spectra Maps. Journal of Spectroscopy No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-998743
American Medical Association (AMA)
Buchwald, Tomasz& Kozielski, Marek& Szybowicz, Mirosław. Determination of Collagen Fibers Arrangement in Bone Tissue by Using Transformations of Raman Spectra Maps. Journal of Spectroscopy. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-998743
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-998743