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Lactoferrin Levels in the Gastric Tissue of Helicobacter pylori-Positive and -Negative Patients and Its Effect on Anemia
Joint Authors
Doğan, Yaşar
Erkan, Tülay
Önal, Zerrin
Usta, Merve
Doğusoy, Gülen
Çokuğraş, Fügen Çullu
Kutlu, Tufan
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-19
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Aim.
To determine gastric tissue lactoferrin (Lf) levels of Helicobacter pylori- (Hp-) positive and -negative patients and its effect on anemia.
Methods.
Cases in which initial presentation was of abdominal pain and that were Hp-positive at endoscopy were included.
Hp-positive cases and -negative controls were divided into two groups.
Results.
The study included 64 cases (average: 10.2±0.4 years, 39 male and 25 female).
Lf levels were subsequently studied on 61 cases.
45 (73.8%) of these were Hp-positive, while 16 (22.2%) were Hp-negative.
In Hp-positive cases, mean staining percentages and density of glands in the antral mucosa were 45.5±4.7% and 1.9±0.1, respectively.
Hp-negative cases showed significantly different values of 17.8±4.5% and 1.3±0.2, respectively.
Hemoglobin and serum ferritin values of Hp-positive cases were 12.7±0.2 g/dL and 32.5±2 ng/mL, but these were comparable with Hp-negative cases (12.6±0.1 g/dL and 30.7±4.4 ng/mL).
Conclusions.
Tissue Lf was significantly higher in Hp-positive cases compared to Hp-negative cases, but no difference was observed between the two groups with regards to hemoglobin and ferritin level.
As a result, it is difficult to say that this rise in Lf plays a role in the development of iron deficiency anemia in Hp-positive patients.
American Psychological Association (APA)
Doğan, Yaşar& Erkan, Tülay& Önal, Zerrin& Usta, Merve& Doğusoy, Gülen& Çokuğraş, Fügen Çullu…[et al.]. 2012. Lactoferrin Levels in the Gastric Tissue of Helicobacter pylori-Positive and -Negative Patients and Its Effect on Anemia. Mediators of Inflammation،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-998853
Modern Language Association (MLA)
Doğan, Yaşar…[et al.]. Lactoferrin Levels in the Gastric Tissue of Helicobacter pylori-Positive and -Negative Patients and Its Effect on Anemia. Mediators of Inflammation No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-998853
American Medical Association (AMA)
Doğan, Yaşar& Erkan, Tülay& Önal, Zerrin& Usta, Merve& Doğusoy, Gülen& Çokuğraş, Fügen Çullu…[et al.]. Lactoferrin Levels in the Gastric Tissue of Helicobacter pylori-Positive and -Negative Patients and Its Effect on Anemia. Mediators of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-998853
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-998853