![](/images/graphics-bg.png)
The Importance of the Nurse Cells and Regulatory Cells in the Control of T Lymphocyte Responses
المؤلفون المشاركون
Reyes García, María Guadalupe
García Tamayo, Fernando
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-26
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
T lymphocytes from the immune system are bone marrow-derived cells whose development and activities are carefully supervised by two sets of accessory cells.
In the thymus, the immature young T lymphocytes are engulfed by epithelial “nurse cells” and retained in vacuoles, where most of them (95%) are negatively selected and removed when they have an incomplete development or express high affinity autoreactive receptors.
The mature T lymphocytes that survive to this selection process leave the thymus and are controlled in the periphery by another subpopulation of accessory cells called “regulatory cells,” which reduce any excessive immune response and the risk of collateral injuries to healthy tissues.
By different times and procedures, nurse cells and regulatory cells control both the development and the functions of T lymphocyte subpopulations.
Disorders in the T lymphocytes development and migration have been observed in some parasitic diseases, which disrupt the thymic microenvironment of nurse cells.
In other cases, parasites stimulate rather than depress the functions of regulatory T cells decreasing T-mediated host damages.
This paper is a short review regarding some features of these accessory cells and their main interactions with T immature and mature lymphocytes.
The modulatory role that neurotransmitters and hormones play in these interactions is also revised.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Reyes García, María Guadalupe& García Tamayo, Fernando. 2012. The Importance of the Nurse Cells and Regulatory Cells in the Control of T Lymphocyte Responses. BioMed Research International،Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-1004091
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Reyes García, María Guadalupe& García Tamayo, Fernando. The Importance of the Nurse Cells and Regulatory Cells in the Control of T Lymphocyte Responses. BioMed Research International No. 2013 (2013), pp.1-15.
https://search.emarefa.net/detail/BIM-1004091
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Reyes García, María Guadalupe& García Tamayo, Fernando. The Importance of the Nurse Cells and Regulatory Cells in the Control of T Lymphocyte Responses. BioMed Research International. 2012. Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-1004091
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1004091
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)