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The Study on Biocompatibility of Porous nHAPLGA Composite Scaffolds for Tissue Engineering with Rabbit Chondrocytes In Vitro
المؤلفون المشاركون
Zeng, Yanjun
Chen, Lei
Zhu, Wei-Min
Fei, Zhi-Qiang
Chen, Jie-Lin
Xiong, Jian-Yi
Zhang, Ju-Feng
Duan, Li
Huang, Jianghong
Liu, Zhiyong
Wang, Daping
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-27
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
To examine the biocompatibility of a novel nanohydroxyapatite/poly[lactic-co-glycolic acid] (nHA/PLGA) composite and evaluate its feasibility as a scaffold for cartilage tissue engineering.
Methods.
Chondrocytes of fetal rabbit were cultured with nHA/PLGA scaffold in vitro and the cell viability was assessed by MTT assay first.
Cells adhering to nHA/PLGA scaffold were then observed by inverted microscope and scanning electron microscope (SEM).
The cell cycle profile was analyzed by flow cytometry.
Results.
The viability of the chondrocytes on the scaffold was not affected by nHA/PLGA comparing with the control group as it was shown by MTT assay.
Cells on the surface and in the pores of the scaffold increased in a time-dependent manner.
Results obtained from flow cytometry showed that there was no significant difference in cell cycle profiles between the coculture group and control (P>0.05).
Conclusion.
The porous nHA/PLGA composite scaffold is a biocompatible and good kind of scaffold for cartilage tissue engineering.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Lei& Zhu, Wei-Min& Fei, Zhi-Qiang& Chen, Jie-Lin& Xiong, Jian-Yi& Zhang, Ju-Feng…[et al.]. 2013. The Study on Biocompatibility of Porous nHAPLGA Composite Scaffolds for Tissue Engineering with Rabbit Chondrocytes In Vitro. BioMed Research International،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1004255
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Lei…[et al.]. The Study on Biocompatibility of Porous nHAPLGA Composite Scaffolds for Tissue Engineering with Rabbit Chondrocytes In Vitro. BioMed Research International No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1004255
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Lei& Zhu, Wei-Min& Fei, Zhi-Qiang& Chen, Jie-Lin& Xiong, Jian-Yi& Zhang, Ju-Feng…[et al.]. The Study on Biocompatibility of Porous nHAPLGA Composite Scaffolds for Tissue Engineering with Rabbit Chondrocytes In Vitro. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1004255
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1004255
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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