Effect of Intermittent Low-Frequency Electrical Stimulation on the Rat Gastrocnemius Muscle
المؤلفون المشاركون
Tsutaki, Arata
Ogasawara, Riki
Kobayashi, Koji
Lee, Kihyuk
Kouzaki, Karina
Nakazato, Koichi
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-09
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Low-frequency neuromuscular electrical stimulation (NMES) has been used as an endurance exercise model.
This study aimed to test whether low-frequency NMES increases the phosphorylation of anabolic signaling molecules and induces skeletal muscle hypertrophy, as seen with high-frequency NMES.
Using Sprague-Dawley rats, 1 bout of exercise (with dissection done immediately (Post0) and 3 h (Post3) after exercise) and another 6 sessions of training were performed.
All experimental groups consisted of high- and low-frequency stimulation (HFS: 100 Hz; LFS: 10 Hz).
Periodic acid-Schiff (PAS) staining was conducted to investigate type II fiber activation, and western blot analysis (WB) was conducted to examine whether NMES leads to anabolic intracellular signaling.
At first, we examined the acute effect of exercise.
PAS staining revealed that glycogen depletion occurred in both type I and type II fibers.
WB results demonstrated that p70S6K phosphorylation was significantly increased by HFS, but there was no significant difference with LFS.
In contrast, ERK 1/2 phosphorylation was increased by LFS at Post0.
In the 6-session training, the wet weight and myofibrillar protein were significantly increased by both HFS and LFS.
In conclusion, LFS has a similar anabolic effect for skeletal muscle hypertrophy as HFS, but the mediating signaling pathway might differ.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tsutaki, Arata& Ogasawara, Riki& Kobayashi, Koji& Lee, Kihyuk& Kouzaki, Karina& Nakazato, Koichi. 2013. Effect of Intermittent Low-Frequency Electrical Stimulation on the Rat Gastrocnemius Muscle. BioMed Research International،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1004409
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tsutaki, Arata…[et al.]. Effect of Intermittent Low-Frequency Electrical Stimulation on the Rat Gastrocnemius Muscle. BioMed Research International No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1004409
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tsutaki, Arata& Ogasawara, Riki& Kobayashi, Koji& Lee, Kihyuk& Kouzaki, Karina& Nakazato, Koichi. Effect of Intermittent Low-Frequency Electrical Stimulation on the Rat Gastrocnemius Muscle. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1004409
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1004409
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر