Immunogenic Cell Death: Can It Be Exploited in PhotoDynamic Therapy for Cancer?
المؤلفون المشاركون
Dini, Luciana
Panzarini, Elisa
Inguscio, Valentina
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-18، 18ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-30
دولة النشر
مصر
عدد الصفحات
18
التخصصات الرئيسية
الملخص EN
Immunogenic Cell Death (ICD) could represent the keystone in cancer management since tumor cell death induction is crucial as well as the control of cancer cells revival after neoplastic treatment.
In this context, the immune system plays a fundamental role.
The concept of Damage-Associated Molecular Patterns (DAMPs) has been proposed to explain the immunogenic potential of stressed or dying/dead cells.
ICD relies on DAMPs released by or exposed on dying cells.
Once released, DAMPs are sensed by immune cells, in particular Dendritic Cells (DCs), acting as activators of Antigen-Presenting Cells (APCs), that in turn stimulate both innate and adaptive immunity.
On the other hand, by exposing DAMPs, dying cancer cells change their surface composition, recently indicated as vital for the stimulation of the host immune system and the control of residual ill cells.
It is well established that PhotoDynamic Therapy (PDT) for cancer treatment ignites the immune system to elicit a specific antitumor immunity, probably linked to its ability in inducing exposure/release of certain DAMPs, as recently suggested.
In the present paper, we discuss the DAMPs associated with PDT and their role in the crossroad between cancer cell death and immunogenicity in PDT.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Panzarini, Elisa& Inguscio, Valentina& Dini, Luciana. 2012. Immunogenic Cell Death: Can It Be Exploited in PhotoDynamic Therapy for Cancer?. BioMed Research International،Vol. 2013, no. 2013, pp.1-18.
https://search.emarefa.net/detail/BIM-1004419
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Panzarini, Elisa…[et al.]. Immunogenic Cell Death: Can It Be Exploited in PhotoDynamic Therapy for Cancer?. BioMed Research International No. 2013 (2013), pp.1-18.
https://search.emarefa.net/detail/BIM-1004419
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Panzarini, Elisa& Inguscio, Valentina& Dini, Luciana. Immunogenic Cell Death: Can It Be Exploited in PhotoDynamic Therapy for Cancer?. BioMed Research International. 2012. Vol. 2013, no. 2013, pp.1-18.
https://search.emarefa.net/detail/BIM-1004419
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1004419
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر