Elastin-Coated Biodegradable Photopolymer Scaffolds for Tissue Engineering Applications
المؤلفون المشاركون
Barenghi, Rossella
Beke, Szabolcs
Romano, Ilaria
Gavazzo, Paola
Farkas, Balázs
Vassalli, Massimo
Brandi, Fernando
Scaglione, Silvia
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-10-23
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
One of the main open issues in modern vascular surgery is the nonbiodegradability of implants used for stent interventions, which can lead to small caliber-related thrombosis and neointimal hyperplasia.
Some new, resorbable polymeric materials have been proposed to substitute traditional stainless-steel stents, but so far they were affected by poor mechanical properties and low biocompatibility.
In this respect, a new material, polypropylene fumarate (PPF), may be considered as a promising candidate to implement the development of next generation stents, due to its complete biodegradability, and excellent mechanical properties and the ease to be precisely patterned.
Besides all these benefits, PPF has not been tested yet for vascular prosthesis, mainly because it proved to be almost inert, while the ability to elicit a specific biological function would be of paramount importance in such critical surgery applications.
Here, we propose a biomimetic functionalization process, aimed at obtaining specific bioactivation and thus improved cell-polymer interaction.
Porous PPF-based scaffolds produced by deep-UV photocuring were coated by elastin and the functionalized scaffolds were extensively characterized, revealing a stable bound between the protein and the polymer surface.
Both 3T3 and HUVEC cell lines were used for in vitro tests displaying an enhancement of cells adhesion and proliferation on the functionalized scaffolds.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Barenghi, Rossella& Beke, Szabolcs& Romano, Ilaria& Gavazzo, Paola& Farkas, Balázs& Vassalli, Massimo…[et al.]. 2014. Elastin-Coated Biodegradable Photopolymer Scaffolds for Tissue Engineering Applications. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1016406
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Barenghi, Rossella…[et al.]. Elastin-Coated Biodegradable Photopolymer Scaffolds for Tissue Engineering Applications. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1016406
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Barenghi, Rossella& Beke, Szabolcs& Romano, Ilaria& Gavazzo, Paola& Farkas, Balázs& Vassalli, Massimo…[et al.]. Elastin-Coated Biodegradable Photopolymer Scaffolds for Tissue Engineering Applications. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1016406
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1016406
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر