Cadmium Increases the Sensitivity of Adolescent Female Mice to Nicotine-Related Behavioral Deficits
المؤلفون المشاركون
Adeniyi, Philip Adeyemi
Olatunji, Babawale Peter
Ishola, Azeez Olakunle
Ajonijebu, Duyilemi Chris
Ogundele, Olalekan Michael
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-11-13
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
This study investigates spatial and nonspatial working memory, anxiety related behavior, and motor activities in cadmium and/or nicotine exposed female adolescent mice.
P28 female adolescent mice (albino strain) were divided into four groups of five (n=5) mice each.
A set of mice (Nic) received subcutaneous nicotine (2.0 mg/kg) while a separate set (Cd) was treated with 2.0 mg/kg cadmium (subcutaneous).
For the combined treatments of cadmium and nicotine, we administered 2.0 mg/kg Nicotine and 2.0 mg/kg of Cd.
Subsequently, a separate group of animals (n=5; control) received normal saline.
The total duration of treatment for all groups was 28 days (P28–P56).
At P56, the treatment was discontinued, after which the animals were examined in behavioural tests.
Nicotine and cadmium increased the metabolism and food intake in the female adolescent mice.
This also corresponded to an increase in weight when compared with the control.
However, a combined nicotine-cadmium treatment induced a decline in weight of the animals versus the control.
Also, nicotine administration increased the motor function, while cadmium and nicotine-cadmium treatment caused a decline in motor activity.
Both nicotine and cadmium induced a reduction in memory index; however, nicotine-cadmium treatment induced the most significant decrease in nonspatial working memory.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Adeniyi, Philip Adeyemi& Olatunji, Babawale Peter& Ishola, Azeez Olakunle& Ajonijebu, Duyilemi Chris& Ogundele, Olalekan Michael. 2014. Cadmium Increases the Sensitivity of Adolescent Female Mice to Nicotine-Related Behavioral Deficits. Behavioural Neurology،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1016677
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Adeniyi, Philip Adeyemi…[et al.]. Cadmium Increases the Sensitivity of Adolescent Female Mice to Nicotine-Related Behavioral Deficits. Behavioural Neurology No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1016677
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Adeniyi, Philip Adeyemi& Olatunji, Babawale Peter& Ishola, Azeez Olakunle& Ajonijebu, Duyilemi Chris& Ogundele, Olalekan Michael. Cadmium Increases the Sensitivity of Adolescent Female Mice to Nicotine-Related Behavioral Deficits. Behavioural Neurology. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1016677
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1016677
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر