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Ethanolic Extract of Butea monosperma Leaves Elevate Blood Insulin Level in Type 2 Diabetic Rats, Stimulate Insulin Secretion in Isolated Rat Islets, and Enhance Hepatic Glycogen Formation
المؤلفون المشاركون
Samad, Mehdi Bin
Kabir, Ashraf Ul
D'Costa, Ninadh Malrina
Akhter, Farjana
Ahmed, Arif
Jahan, Mohammad Rajib
Hannan, J. M. A.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-31
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
We measured a vast range of parameters, in an attempt to further elucidate previously claimed antihyperglycemic activity of Butea monosperma.
Our study clearly negates the possibility of antidiabetic activity by inhibited gastrointestinal enzyme action or by reduced glucose absorption.
Reduction of fasting and postprandial glucose level was reconfirmed (P<0.05).
Improved serum lipid profile via reduced low density lipoprotein (LDL), cholesterol, triglycerides (TG), and increased high density lipoprotein (HDL) was also reestablished (P<0.05).
Significant insulin secretagogue activity of B.
monosperma was found in serum insulin assay of B.
monosperma treated type 2 diabetic rats (P<0.01).
This was further ascertained by our study on insulin secretion on isolated rat islets (P<0.05).
Improved sensitivity of glucose was shown by the significant increase in hepatic glycogen deposition (P<0.05).
Hence, we concluded that antihyperglycemic activity of B.
monosperma was mediated by enhanced insulin secretion and enhanced glycogen formation in the liver.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Samad, Mehdi Bin& Kabir, Ashraf Ul& D'Costa, Ninadh Malrina& Akhter, Farjana& Ahmed, Arif& Jahan, Mohammad Rajib…[et al.]. 2014. Ethanolic Extract of Butea monosperma Leaves Elevate Blood Insulin Level in Type 2 Diabetic Rats, Stimulate Insulin Secretion in Isolated Rat Islets, and Enhance Hepatic Glycogen Formation. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1018387
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Samad, Mehdi Bin…[et al.]. Ethanolic Extract of Butea monosperma Leaves Elevate Blood Insulin Level in Type 2 Diabetic Rats, Stimulate Insulin Secretion in Isolated Rat Islets, and Enhance Hepatic Glycogen Formation. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-13.
https://search.emarefa.net/detail/BIM-1018387
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Samad, Mehdi Bin& Kabir, Ashraf Ul& D'Costa, Ninadh Malrina& Akhter, Farjana& Ahmed, Arif& Jahan, Mohammad Rajib…[et al.]. Ethanolic Extract of Butea monosperma Leaves Elevate Blood Insulin Level in Type 2 Diabetic Rats, Stimulate Insulin Secretion in Isolated Rat Islets, and Enhance Hepatic Glycogen Formation. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1018387
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1018387
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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