Memory-Enhancing Effects of the Crude Extract of Polygala tenuifolia on Aged Mice
المؤلفون المشاركون
Li, Zongyang
Liu, Yamin
Wang, Liwei
Liu, Xinmin
Chang, Qi
Guo, Zhi
Liao, Yonghong
Pan, Ruile
Fan, Tai-Ping
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-12
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Learning and memory disorders arise from distinct age-associated processes, and aging animals are often used as a model of memory impairment.
The root of Polygala tenuifolia has been commonly used in some Asian countries as memory enhancer and its memory improvement has been reported in various animal models.
However, there is less research to verify its effect on memory functions in aged animals.
Herein, the memory-enhancing effects of the crude extract of Polygala tenuifolia (EPT) on normal aged mice were assessed by Morris water maze (MWM) and step-down passive avoidance tests.
In MWM tests, the impaired spatial memory of the aged mice was partly reversed by EPT (100 and 200 mg/kg; P < 0.05) as compared with the aged control mice.
In step-down tests, the nonspatial memory of the aged mice was improved by EPT (100 and 200 mg/kg; P < 0.05).
Additionally, EPT could increase superoxide dismutase (SOD) and catalase (CAT) activities, inhibit monoamine oxidase (MAO) and acetyl cholinesterase (AChE) activities, and decrease the levels of malondialdehyde (MDA) in the brain tissue of the aged mice.
The results showed that EPT improved memory functions of the aged mice probably via its antioxidant properties and via decreasing the activities of MAO and AChE.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Zongyang& Liu, Yamin& Wang, Liwei& Liu, Xinmin& Chang, Qi& Guo, Zhi…[et al.]. 2014. Memory-Enhancing Effects of the Crude Extract of Polygala tenuifolia on Aged Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1018432
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Zongyang…[et al.]. Memory-Enhancing Effects of the Crude Extract of Polygala tenuifolia on Aged Mice. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1018432
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Zongyang& Liu, Yamin& Wang, Liwei& Liu, Xinmin& Chang, Qi& Guo, Zhi…[et al.]. Memory-Enhancing Effects of the Crude Extract of Polygala tenuifolia on Aged Mice. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1018432
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1018432
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر