Preventive Effects of Collagen Peptide from Deer Sinew on Bone Loss in Ovariectomized Rats
المؤلفون المشاركون
Zhang, He
Dong, Ying
Qi, Bin
Liu, Li
Zhou, Guangxin
Bai, Xueyuan
Yang, Chunhui
Zhao, Daqing
Zhao, Yu
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-01
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Deer sinew (DS) has been used traditionally for various illnesses, and the major active constituent is collagen.
In this study, we assessed the effects of collagen peptide from DS on bone loss in the ovariectomized rats.
Wister female rats were randomly divided into six groups as follows: sham-operated (SHAM), ovariectomized control (OVX), OVX given 1.0 mg/kg/week nylestriol (OVX + N), OVX given 0.4 g/kg/day collagen peptide (OVX + H), OVX given 0.2 g/kg/day collagen peptide (OXV + M), and OVX given 0.1 g/kg/day collagen peptide (OXV + L), respectively.
After 13 weeks of treatment, the rats were euthanized, and the effects of collagen peptide on body weight, uterine weight, bone mineral density (BMD), serum biochemical indicators, bone histomorphometry, and bone mechanics were observed.
The data showed that BMD and concentration of serum hydroxyproline were significantly increased and the levels of serum calcium, phosphorus, and alkaline phosphatase were decreased.
Besides, histomorphometric parameters and mechanical indicators were improved.
However, collagen peptide of DS has no effect on estradiol level, body weight, and uterine weight.
Therefore, these results suggest that the collagen peptide supplementation may also prevent and treat bone loss.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, He& Dong, Ying& Qi, Bin& Liu, Li& Zhou, Guangxin& Bai, Xueyuan…[et al.]. 2014. Preventive Effects of Collagen Peptide from Deer Sinew on Bone Loss in Ovariectomized Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1018759
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, He…[et al.]. Preventive Effects of Collagen Peptide from Deer Sinew on Bone Loss in Ovariectomized Rats. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1018759
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, He& Dong, Ying& Qi, Bin& Liu, Li& Zhou, Guangxin& Bai, Xueyuan…[et al.]. Preventive Effects of Collagen Peptide from Deer Sinew on Bone Loss in Ovariectomized Rats. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1018759
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1018759
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر