Behavioral and Histopathological Study of Changes in Spinal Cord Injured Rats Supplemented with Spirulina platensis
المؤلفون المشاركون
Aziz, Izzuddin
Che Ramli, Muhammad Danial
Mohd Zain, Nurul Suraya
Sanusi, Junedah
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-23
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Spinal cord injury (SCI) is a devastating disease that leads to permanent disability and causes great suffering.
The resulting neurological dysfunction and paralysis is proportional to the severity of the trauma itself.
Spirulina is widely used as a nutritional supplement due to its high protein and antioxidant content.
In the present study, the protective effect of the Spirulina treatment on locomotor function and morphological damage after SCI was investigated.
Seventy Sprague-Dawley (SD) rats were divided into three groups: Sham (laminectomy alone), Control (laminectomy with SCI), and Experimental (laminectomy with SCI +180 mg/kg per day Spirulina platensis).
A laminectomy was performed at T12 and an Inox No.2 modified forceps was used to perform a partial crush injury on the spinal cord.
The rats were then perfused at 3, 7, 14, 21, and 28 days after injury for morphological investigations.
The injured rat spinal cord indicated a presence of hemorrhage, cavity, and necrosis.
Pretreatment with Spirulina significantly improved the locomotor function and showed a significant reduction on the histological changes.
The experimental results observed in this study suggest that treatment with Spirulina platensis possesses potential benefits in improving hind limb locomotor function and reducing morphological damage to the spinal cord.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Aziz, Izzuddin& Che Ramli, Muhammad Danial& Mohd Zain, Nurul Suraya& Sanusi, Junedah. 2014. Behavioral and Histopathological Study of Changes in Spinal Cord Injured Rats Supplemented with Spirulina platensis. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1020359
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Aziz, Izzuddin…[et al.]. Behavioral and Histopathological Study of Changes in Spinal Cord Injured Rats Supplemented with Spirulina platensis. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1020359
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Aziz, Izzuddin& Che Ramli, Muhammad Danial& Mohd Zain, Nurul Suraya& Sanusi, Junedah. Behavioral and Histopathological Study of Changes in Spinal Cord Injured Rats Supplemented with Spirulina platensis. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1020359
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1020359
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر