Synthesis of some new derivatives of pyrrolidine-2-one and studying their antibacterial potentials
المؤلفون المشاركون
Kazim, Sahar A.
Betti, Nadiyah A.
Husayn, Rida Ib.
المصدر
Engineering and Technology Journal
العدد
المجلد 38، العدد 3B (31 مارس/آذار 2020)، ص ص. 128-141، 14ص.
الناشر
تاريخ النشر
2020-03-31
دولة النشر
العراق
عدد الصفحات
14
التخصصات الرئيسية
الموضوعات
الملخص EN
New derivatives of pyrrolidine-2-one have been synthesized through lactamization of γ –butyrolactone (GBL) by hydrazine hydrate (80% ), ethylene diamine and ethanol amine to afford compounds (1-aminopyrrolidin-2-one), (1-(2-aminoethyl)pyrrolidine-2-one) and (1-(2-hydroxyethyl)pyrrolidine-2-one), respectively.
Compound (1-aminopyrrolidin-2-one) underwent several reactions to synthesize the rest of these derivatives.
All synthesized compounds were approved by their FT-IR, 1H-NMR and some by Mass spectra.
The biological activities of these derivatives were evaluated against Escherichia coli and Staphylococcus aureus.
Many of these derivatives showed moderate biological activity against one or both kind of bacteria in comparison to amoxicillin and some showed no biological activity at underwent several reactions to synthesize the rest of these derivatives.
All synthesized compounds were approved by their FT-IR, 1H-NMR and some by Mass spectra.
The biological activities of these derivatives were evaluated against Escherichia coli and Staphylococcus aureus.
Many of these derivatives showed moderate biological activity against one or both kind of bacteria in comparison to amoxicillin and some showed no biological activity at all
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Betti, Nadiyah A.& Husayn, Rida Ib.& Kazim, Sahar A.. 2020. Synthesis of some new derivatives of pyrrolidine-2-one and studying their antibacterial potentials. Engineering and Technology Journal،Vol. 38, no. 3B, pp.128-141.
https://search.emarefa.net/detail/BIM-1020772
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Betti, Nadiyah A.…[et al.]. Synthesis of some new derivatives of pyrrolidine-2-one and studying their antibacterial potentials. Engineering and Technology Journal Vol. 38, no. 3B (2020), pp.128-141.
https://search.emarefa.net/detail/BIM-1020772
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Betti, Nadiyah A.& Husayn, Rida Ib.& Kazim, Sahar A.. Synthesis of some new derivatives of pyrrolidine-2-one and studying their antibacterial potentials. Engineering and Technology Journal. 2020. Vol. 38, no. 3B, pp.128-141.
https://search.emarefa.net/detail/BIM-1020772
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 140-141
رقم السجل
BIM-1020772
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر