Advantages and Disadvantages of Hyperbaric Oxygen Treatment in Mice with Obesity Hyperlipidemia and Steatohepatitis

المؤلفون المشاركون

Tsuneyama, Koichi
Shimada, Tsutomu
Chen, Yen-Chen
Sasaki, Yoshiyuki
Suzuki, Wataru
Iizuka, Seiichi
Nagata, Mitsunobu
Aburada, Masaki
Chen, Shao-Yuan
Fujimoto, Makoto

المصدر

The Scientific World Journal

العدد

المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-12، 12ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2011-11-03

دولة النشر

مصر

عدد الصفحات

12

التخصصات الرئيسية

الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب

الملخص EN

The effect of hyperbaric oxygen treatment (HBOT) was examined using MSG mice, which are an animal model of obesity, hyperlipidemia, diabetes, and nonalcoholic fatty liver disease.

Nineteen MSG male mice were divided into HBOT treated and control groups at 12 weeks of ages.

The HBOT group was treated with hyperbaric oxygen from 12 to 14 weeks (first phase) and then from 16 to 18 weeks (second phase).

Interestingly, the body weight of the HBOT group was significantly lower (P<0.01) than that of the control group.

In contrast, the serum lipid level did not show significant changes between the two groups.

As for the effects of increasing oxidative stress, the liver histology of the HBOT group showed severer cellular damage and aberrant TNF-α expression.

HBOT has the advantage of improving obesity in patients with metabolic syndrome, but the fault of causing organ damage by increasing oxidative stress.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Tsuneyama, Koichi& Chen, Yen-Chen& Fujimoto, Makoto& Sasaki, Yoshiyuki& Suzuki, Wataru& Shimada, Tsutomu…[et al.]. 2011. Advantages and Disadvantages of Hyperbaric Oxygen Treatment in Mice with Obesity Hyperlipidemia and Steatohepatitis. The Scientific World Journal،Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-1027873

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Tsuneyama, Koichi…[et al.]. Advantages and Disadvantages of Hyperbaric Oxygen Treatment in Mice with Obesity Hyperlipidemia and Steatohepatitis. The Scientific World Journal No. 2011 (2011), pp.1-12.
https://search.emarefa.net/detail/BIM-1027873

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Tsuneyama, Koichi& Chen, Yen-Chen& Fujimoto, Makoto& Sasaki, Yoshiyuki& Suzuki, Wataru& Shimada, Tsutomu…[et al.]. Advantages and Disadvantages of Hyperbaric Oxygen Treatment in Mice with Obesity Hyperlipidemia and Steatohepatitis. The Scientific World Journal. 2011. Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-1027873

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1027873