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Analgesic and Anti-Inflammatory Activities of Methanol Extract of Ficus pumila L. in Mice
المؤلفون المشاركون
Chang, Yuan-Shiun
Peng, Wen-Huang
Liao, Chi-Ren
Kao, Chun-Pin
Lai, Shang-Chih
Ho, Yu-Ling
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-05-14
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
This study investigated possible analgesic and anti-inflammatory mechanisms of the methanol extract of Ficus pumila (FPMeOH).
Analgesic effects were evaluated in two models including acetic acid-induced writhing response and formalin-induced paw licking.
The results showed FPMeOH decreased writhing response in the acetic acid assay and licking time in the formalin test.
The anti-inflammatory effect was evaluated by λ-carrageenan-induced mouse paw edema and histopathological analyses.
FPMeOH significantly decreased the volume of paw edema induced by λ-carrageenan.
Histopathologically, FPMeOH abated the level of tissue destruction and swelling of the edema paws.
This study indicated anti-inflammatory mechanism of FPMeOH may be due to declined levels of NO and MDA in the edema paw through increasing the activities of SOD, GPx, and GRd in the liver.
Additionally, FPMeOH also decreased the level of inflammatory mediators such as IL-1β, TNF-α, and COX-2.
HPLC fingerprint was established and the contents of three active ingredients, rutin, luteolin, and apigenin, were quantitatively determined.
This study provided evidence for the classical treatment of Ficus pumila in inflammatory diseases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liao, Chi-Ren& Kao, Chun-Pin& Peng, Wen-Huang& Chang, Yuan-Shiun& Lai, Shang-Chih& Ho, Yu-Ling. 2012. Analgesic and Anti-Inflammatory Activities of Methanol Extract of Ficus pumila L. in Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-1028259
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liao, Chi-Ren…[et al.]. Analgesic and Anti-Inflammatory Activities of Methanol Extract of Ficus pumila L. in Mice. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-1028259
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liao, Chi-Ren& Kao, Chun-Pin& Peng, Wen-Huang& Chang, Yuan-Shiun& Lai, Shang-Chih& Ho, Yu-Ling. Analgesic and Anti-Inflammatory Activities of Methanol Extract of Ficus pumila L. in Mice. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-1028259
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1028259
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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