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Impact of Global Normalization in fMRI Acupuncture Studies
المؤلفون المشاركون
Yang, Yang
Zhu, Yuanqiang
von Deneen, Karen M.
Jin, Lingmin
Dong, Minghao
Yang, Xuejuan
Gong, Qiyong
Tian, Jie
Sun, Jinbo
Qin, Wei
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-22، 22ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-17
دولة النشر
مصر
عدد الصفحات
22
التخصصات الرئيسية
الملخص EN
Global normalization is often used as a preprocessing step for dispelling the “nuisance effects.” However, it has been shown in cognitive and emotion tasks that this preprocessing step might greatly distort statistical results when the orthogonality assumption of global normalization is violated.
The present study examines this issue in fMRI acupuncture studies.
Thirty healthy subjects were recruited to evaluate the impacts of the global normalization on the BOLD responses evoked by acupuncture stimulation during De-qi sensation and tactile stimulation during nonpainful sensations.
To this end, we compared results by conducting global normalization (PSGS) and not conducting global normalization (NO PSGS) based on a proportional scaling model.
The orthogonality assumption of global normalization was violated, and significant changes between BOLD responses for NO PSGS and PSGS were shown in most subjects.
Extensive deactivations of acupuncture in fMRI were the non-specifically pernicious consequences of global normalization.
The central responses of acupuncture during De-qi are non-specifically activation-dominant at the somatosensory-related brain network, whose statistical power is specifically enhanced by PSGS.
In conclusion, PSGS should be unjustified for acupuncture studies in fMRI.
The differences including the global normalization or not may partly contribute to conflicting results and interpretations in previous fMRI acupuncture studies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sun, Jinbo& Qin, Wei& Jin, Lingmin& Dong, Minghao& Yang, Xuejuan& Zhu, Yuanqiang…[et al.]. 2012. Impact of Global Normalization in fMRI Acupuncture Studies. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-22.
https://search.emarefa.net/detail/BIM-1028327
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sun, Jinbo…[et al.]. Impact of Global Normalization in fMRI Acupuncture Studies. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-22.
https://search.emarefa.net/detail/BIM-1028327
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sun, Jinbo& Qin, Wei& Jin, Lingmin& Dong, Minghao& Yang, Xuejuan& Zhu, Yuanqiang…[et al.]. Impact of Global Normalization in fMRI Acupuncture Studies. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-22.
https://search.emarefa.net/detail/BIM-1028327
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1028327
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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