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Effects of Eurycoma longifolia on Testosterone Level and Bone Structure in an Aged Orchidectomised Rat Model
المؤلفون المشاركون
Shuid, Ahmad Nazrun
Ima-Nirwana, Soelaiman
Tajul Ariff, Abdul Shukor
Pramanik, J.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-26
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Testosterone replacement is the choice of treatment in androgen-deficient osteoporosis.
However, long-term use of testosterone is potentially carcinogenic.
Eurycoma longifolia (EL) has been reported to enhance testosterone level and prevent bone calcium loss but there is a paucity of research regarding its effect on the bone structural parameters.
This study was conducted to explore the bone structural changes following EL treatment in normal and androgen-deficient osteoporosis rat model.
Thirty-six male Sprague-Dawley rats aged 12 months were divided into normal control, normal rat supplemented with EL, sham-operated, orchidectomised-control, orchidectomised with testosterone replacement, and orchidectomised with EL supplementation groups.
Testosterone serum was measured both before and after the completion of the treatment.
After 6 weeks of the treatment, the femora were processed for bone histomorphometry.
Testosterone replacement was able to raise the testosterone level and restore the bone volume of orchidectomised rats.
EL supplementation failed to emulate both these testosterone actions.
The inability of EL to do so may be related to the absence of testes in the androgen deficient osteoporosis model for EL to stimulate testosterone production.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tajul Ariff, Abdul Shukor& Ima-Nirwana, Soelaiman& Pramanik, J.& Shuid, Ahmad Nazrun. 2012. Effects of Eurycoma longifolia on Testosterone Level and Bone Structure in an Aged Orchidectomised Rat Model. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1028558
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tajul Ariff, Abdul Shukor…[et al.]. Effects of Eurycoma longifolia on Testosterone Level and Bone Structure in an Aged Orchidectomised Rat Model. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-1028558
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tajul Ariff, Abdul Shukor& Ima-Nirwana, Soelaiman& Pramanik, J.& Shuid, Ahmad Nazrun. Effects of Eurycoma longifolia on Testosterone Level and Bone Structure in an Aged Orchidectomised Rat Model. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1028558
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1028558
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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