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Ginsenoside-Rg1 Protects the Liver against Exhaustive Exercise-Induced Oxidative Stress in Rats
المؤلفون المشاركون
Korivi, Mallikarjuna
Hou, Chien-Wen
Lee, Shin-Da
Hsu, Ming-Fen
Yu, Szu-Hsien
Chen, Chung-Yu
Liu, Yung-Yang
Huang, Chih-Yang
Kuo, Chia-Hua
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-09-20
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Despite regular exercise benefits, acute exhaustive exercise elicits oxidative damage in liver.
The present study determined the hepatoprotective properties of ginsenoside-Rg1 against exhaustive exercise-induced oxidative stress in rats.
Forty rats were assigned into vehicle and ginsenoside-Rg1 groups (0.1 mg/kg bodyweight).
After 10-week treatment, ten rats from each group performed exhaustive swimming.
Estimated oxidative damage markers, including thiobarbituric acid reactive substance (TBARS) (67%) and protein carbonyls (56%), were significantly (P<0.01) elevated after exhaustive exercise but alleviated in ginsenoside-Rg1 pretreated rats.
Furthermore, exhaustive exercise drastically decreased glutathione (GSH) content (~79%) with concurrent decreased superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities.
However, these changes were attenuated in Rg1 group.
Additionally, increased xanthine oxidase (XO) activity and nitric oxide (NO) levels after exercise were also inhibited by Rg1 pretreatment.
For the first time, our findings provide strong evidence that ginsenoside-Rg1 can protect the liver against exhaustive exercise-induced oxidative damage.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Korivi, Mallikarjuna& Hou, Chien-Wen& Huang, Chih-Yang& Lee, Shin-Da& Hsu, Ming-Fen& Yu, Szu-Hsien…[et al.]. 2011. Ginsenoside-Rg1 Protects the Liver against Exhaustive Exercise-Induced Oxidative Stress in Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-1028629
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Korivi, Mallikarjuna…[et al.]. Ginsenoside-Rg1 Protects the Liver against Exhaustive Exercise-Induced Oxidative Stress in Rats. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-1028629
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Korivi, Mallikarjuna& Hou, Chien-Wen& Huang, Chih-Yang& Lee, Shin-Da& Hsu, Ming-Fen& Yu, Szu-Hsien…[et al.]. Ginsenoside-Rg1 Protects the Liver against Exhaustive Exercise-Induced Oxidative Stress in Rats. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-1028629
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1028629
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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