Difference of Morphology and Immunophenotype between Central and Peripheral Squamous Cell Carcinomas of the Lung
المؤلفون المشاركون
Sano, Hisao
Egashira, Ryoko
Tabata, Kazuhiro
Tanaka, Tomonori
Kashima, Yukio
Hori, Takashi
Nunomura, Sayuri
Fukuoka, Junya
Nakayama, Toshiyuki
Hayashi, Tomayoshi
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-08-28
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
Recent agents, that is, pemetrexed and bevacizumab, have shown reproductive negative association between squamous histology.
According to these agents' effectiveness, ruling out of the squamous histology is a significant issue for surgical pathologists.
Several articles have proposed the distinction of peripheral type from central type of squamous cell carcinoma (SqCC) due to its similarity to adenocarcinoma, although little evidence to support the difference between these two types was published.
In this study, we compared the clinicopathologic findings of central and peripheral pulmonary SqCCs.
Material and Methods.
15 central and 35 peripheral types of SqCC from 2005 to 2010 were examined.
Twelve morphological features were scored based on their intensity in the original H&E slides, and then, tissue microarray holding triplicated cores from 43 cases was immunohistochemically examined for cytokeratin (CK)7, CK14, TTF-1, Napsin A, p63, CK34βE12, CK5/6, and p53.
Result.
Most of the histological findings did not separate central and peripheral SqCCs; only the presence of emphysema, interstitial fibrosis, and entrapped pneumocytes inside the tumor showed statistic predominance in peripheral SqCC.
This is the first immunophenotypic research in the central and peripheral types of SqCC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hayashi, Tomayoshi& Sano, Hisao& Egashira, Ryoko& Tabata, Kazuhiro& Tanaka, Tomonori& Nakayama, Toshiyuki…[et al.]. 2013. Difference of Morphology and Immunophenotype between Central and Peripheral Squamous Cell Carcinomas of the Lung. BioMed Research International،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1030141
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hayashi, Tomayoshi…[et al.]. Difference of Morphology and Immunophenotype between Central and Peripheral Squamous Cell Carcinomas of the Lung. BioMed Research International No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-1030141
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hayashi, Tomayoshi& Sano, Hisao& Egashira, Ryoko& Tabata, Kazuhiro& Tanaka, Tomonori& Nakayama, Toshiyuki…[et al.]. Difference of Morphology and Immunophenotype between Central and Peripheral Squamous Cell Carcinomas of the Lung. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1030141
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1030141
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر