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Improved Early Postresuscitation EEG Activity for Animals Treated with Hypothermia Predicted 96 hr Neurological Outcome and Survival in a Rat Model of Cardiac Arrest
المؤلفون المشاركون
Li, Yongqin
Song, Feng-Qing
Sun, Lei-Lei
Lei, Ling-Yan
Gan, Wei-Ni
Chen, Meng-Hua
Chen, Bihua
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-04
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Purpose.
To investigate the effect of hypothermia on 96 hr neurological outcome and survival by quantitatively characterizing early postresuscitation EEG in a rat model of cardiac arrest.
Materials and Methods.
In twenty male Sprague-Dawley rats, cardiac arrest was induced through high frequency transesophageal cardiac pacing.
Cardiopulmonary resuscitation was initiated after 5 mins untreated arrest.
Immediately after resuscitation, animals were randomized to either 2 hrs of hypothermia (N=10) or normothermia (N=10).
EEG, ECG, aortic pressure, and core temperature were continuously recorded for 6 hrs.
Neurological outcome was evaluated daily during the 96 hrs postresuscitation period.
Results.
No differences in the baseline measurements and resuscitation outcome were observed between groups.
However, 96 hr neurological deficit score (204 ± 255 versus 500 ± 0, P=0.005) and survival (6/10 versus 0/10, P=0.011) were significantly better in the hypothermic group.
Quantitative analysis of early postresuscitation EEG revealed that burst frequency and spectrum entropy were greatly improved in the hypothermic group and correlated with 96 hr neurological outcome and survival.
Conclusion.
The improved burst frequency during burst suppression period and preserved spectrum entropy after restoration of continuous background EEG activity for animals treated with hypothermia predicted favorable neurological outcome and survival in this rat model of cardiac arrest.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Bihua& Song, Feng-Qing& Sun, Lei-Lei& Lei, Ling-Yan& Gan, Wei-Ni& Chen, Meng-Hua…[et al.]. 2013. Improved Early Postresuscitation EEG Activity for Animals Treated with Hypothermia Predicted 96 hr Neurological Outcome and Survival in a Rat Model of Cardiac Arrest. BioMed Research International،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1030355
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Bihua…[et al.]. Improved Early Postresuscitation EEG Activity for Animals Treated with Hypothermia Predicted 96 hr Neurological Outcome and Survival in a Rat Model of Cardiac Arrest. BioMed Research International No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1030355
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Bihua& Song, Feng-Qing& Sun, Lei-Lei& Lei, Ling-Yan& Gan, Wei-Ni& Chen, Meng-Hua…[et al.]. Improved Early Postresuscitation EEG Activity for Animals Treated with Hypothermia Predicted 96 hr Neurological Outcome and Survival in a Rat Model of Cardiac Arrest. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1030355
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1030355
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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