Diffusion-Weighted Magnetic Resonance Application in Response Prediction before, during, and after Neoadjuvant Radiochemotherapy in Primary Rectal Cancer Carcinoma
المؤلفون المشاركون
Magnante, Anna Lisa
Ciolina, Maria
De Cecco, Carlo Nicola
Rengo, Marco
Raffetto, Nicola
Redler, Adriano
Tombolini, Vincenzo
De Felice, Francesca
Musio, Daniela
Laghi, Andrea
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-10
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Introduction.
Our interest was to monitor treatment response using ADC value to predict response of rectal tumour to preoperative radiochemotherapy.
Materials and Methods.
Twenty-two patients were treated with long course of radiochemotherapy, followed by surgery.
Patients were examined by diffusion-weighted imaging MRI at three-time points (prior, during, and after radiochemotherapy) and were classified as responders and nonresponders.
Results.
A statistical significant correlation was found between preradiochemotherapy ADC values and during treatment ADC values, in responders (F=21.50, P value <0.05).
An increase in ADC value during treatment was predictive of at least a partial response.
Discussion.
Response of tumour to neoadjuvant therapy cannot be easily evaluated, and such capability might be of great importance in clinical practice, because the number of irradiated and operated patients may be superior to the number of who will really benefit from this multimodal treatment.
A reliable prediction of the final clinical TN stage would allow radiotherapist to adapt multidisciplinary approach to a less invasive management, sparing surgical procedure in responder patients or even allowing an early surgery in nonresponders, which would significantly reduce radiochemotherapy related toxicity.
Conclusion.
Early evaluation of response during neoadjuvant radiochemotherapy treatment shows great promise to predict tumour response.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Musio, Daniela& De Felice, Francesca& Magnante, Anna Lisa& Ciolina, Maria& De Cecco, Carlo Nicola& Rengo, Marco…[et al.]. 2013. Diffusion-Weighted Magnetic Resonance Application in Response Prediction before, during, and after Neoadjuvant Radiochemotherapy in Primary Rectal Cancer Carcinoma. BioMed Research International،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1030862
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Musio, Daniela…[et al.]. Diffusion-Weighted Magnetic Resonance Application in Response Prediction before, during, and after Neoadjuvant Radiochemotherapy in Primary Rectal Cancer Carcinoma. BioMed Research International No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-1030862
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Musio, Daniela& De Felice, Francesca& Magnante, Anna Lisa& Ciolina, Maria& De Cecco, Carlo Nicola& Rengo, Marco…[et al.]. Diffusion-Weighted Magnetic Resonance Application in Response Prediction before, during, and after Neoadjuvant Radiochemotherapy in Primary Rectal Cancer Carcinoma. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1030862
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1030862
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر