Lactobacilli Reduce Chemokine IL-8 Production in Response to TNF-α and Salmonella Challenge of Caco-2 Cells
المؤلفون المشاركون
Qin, Yan-Qing
Yin, Rong-Lan
Ye, Fei
Liu, Hong-Feng
Wang, Mao-Peng
Sun, Yang
Li, Xiao
Tian, Ming-Yao
Jin, Ning-Yi
Li, Chang
Du, Shouwen
Ren, Dayong
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-28
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The probiotic properties of two selected lactobacilli strains were assessed.
L.
salivarius and L.
plantarum displayed higher hydrophobicity (48% and 54%, resp.) and coaggregation ability with four pathogens (from 7.9% to 57.5%).
L.
salivarius and L.
plantarum had good inhibitory effects on S.
aureus (38.2% and 49.5%, resp.) attachment to Caco-2 cells.
Live lactobacilli strains and their conditioned media effectively inhibited IL-8 production (<14.6 pg/mL) in TNF-α-induced Caco-2 cells.
Antibiotic-treated and the sonicated lactobacilli also maintained inhibitory effects (IL-8 production from 5.0 to 36.3 pg/mL); however, the heat-treated lactobacilli lost their inhibitory effects (IL-8 production from 130.2 to 161.0 pg/mL).
These results suggest that both the structural components and the soluble cellular content of lactobacilli have anti-inflammatory effects.
We also found that pretreatment of Caco-2 cells with lactobacilli inhibited S.
typhimurium-induced IL-8 production (<27.3 pg/mL).
However, lactobacilli did not inhibit IL-8 production in Caco-2 cells pretreated with S.
typhimurium.
These results suggest that the tested lactobacilli strains are appropriate for preventing inflammatory diseases caused by enteric pathogens but not for therapy.
In short, L.
salivarius and L.
plantarum are potential candidates for the development of microbial ecological agents and functional foods.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ren, Dayong& Li, Chang& Qin, Yan-Qing& Yin, Rong-Lan& Du, Shouwen& Ye, Fei…[et al.]. 2013. Lactobacilli Reduce Chemokine IL-8 Production in Response to TNF-α and Salmonella Challenge of Caco-2 Cells. BioMed Research International،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1031100
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ren, Dayong…[et al.]. Lactobacilli Reduce Chemokine IL-8 Production in Response to TNF-α and Salmonella Challenge of Caco-2 Cells. BioMed Research International No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1031100
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ren, Dayong& Li, Chang& Qin, Yan-Qing& Yin, Rong-Lan& Du, Shouwen& Ye, Fei…[et al.]. Lactobacilli Reduce Chemokine IL-8 Production in Response to TNF-α and Salmonella Challenge of Caco-2 Cells. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1031100
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1031100
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر