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Pulmonary Innate Immune Response and Melatonin Receptors in the Perinatal Stress
المؤلفون المشاركون
Corrêa, Rosana Rosa Miranda
Vinícius da Silva, Marcos
Rocha, Laura Penna
Guimarães, Camila Souza de Oliveira
Olegário, Janaínna Grazielle Pacheco
Reis, Marlene Antônia dos
Machado, Juliana Reis
المصدر
Journal of Immunology Research
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-01-02
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Objective.
To analyze the cytokines of the innate immune pulmonary response and the capacity for local response to melatonin according to the perinatal stress.
Methods.
49 cases of pediatric autopsies were evaluated, divided according to cause of death, perinatal stress, gestational age, and birth weight.
The percentages of IL-6, C-reactive protein (CRP), IL-1β, TNF-α, and melatonin receptor were evaluated by immunohistochemistry.
Results.
The IL-6 expression was higher in the children showing chronic stress, anoxia, and infection.
The IL-6 expression showed a progressive increase according to the relation between weight and GA.
There was no significant difference in the expression of IL-1β and TNF-α.
The CRP expression was higher in the cases showing chronic stress and premature cases.
The expression of melatonin receptors was significantly higher in the cases showing chronic stress, being more evident in the cases showing infection.
Conclusion.
The cause of death and the type of stress influence the expression in situ of melatonin and cytokines of the innate immune pulmonary response.
The evaluation of IL-6 and CRP may contribute to the understanding of the evolution of neonates with chronic stress.
The greater sensitivity of the lung to melatonin in these cases may indicate an attempt at controlling the immunological response, in an attempt to diminish the harmful effects of stress.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Olegário, Janaínna Grazielle Pacheco& Vinícius da Silva, Marcos& Machado, Juliana Reis& Rocha, Laura Penna& Reis, Marlene Antônia dos& Guimarães, Camila Souza de Oliveira…[et al.]. 2013. Pulmonary Innate Immune Response and Melatonin Receptors in the Perinatal Stress. Journal of Immunology Research،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1031275
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Olegário, Janaínna Grazielle Pacheco…[et al.]. Pulmonary Innate Immune Response and Melatonin Receptors in the Perinatal Stress. Journal of Immunology Research No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-1031275
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Olegário, Janaínna Grazielle Pacheco& Vinícius da Silva, Marcos& Machado, Juliana Reis& Rocha, Laura Penna& Reis, Marlene Antônia dos& Guimarães, Camila Souza de Oliveira…[et al.]. Pulmonary Innate Immune Response and Melatonin Receptors in the Perinatal Stress. Journal of Immunology Research. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1031275
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1031275
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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