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Effects of Chitosan Alkali Pretreatment on the Preparation of Electrospun PCLChitosan Blend Nanofibrous Scaffolds for Tissue Engineering Application
المؤلفون المشاركون
Sultana, Naznin
Roozbahani, Fatemeh
Fauzi Ismail, Ahmad
Nouparvar, Hamed
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-08-29
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Recently, nanofibrous scaffolds have been used in the field of biomedical engineering as wound dressings, tissue engineering scaffolds, and drug delivery applications.
The electrospun nanofibrous scaffolds can be used as carriers for several types of drugs, genes, and growth factors.
PCL is one of the most commonly applied synthetic polymers for medical use because of its biocompatibility and slow biodegradability.
PCL is hydrophobic and has no cell recognition sites on its structure.
Electrospinning of chitosan and PCL blend was investigated in formic acid/acetic acid as the solvent with different PCL/chitosan ratios.
High viscosity of chitosan solutions makes difficulties in the electrospinning process.
Strong hydrogen bonds in a 3D network in acidic condition prevent the movement of polymeric chains exposed to the electrical field.
Consequently, the amount of chitosan in PCL/chitosan blend was limited and more challenging when the concentration of PCL increases.
The treatment of chitosan in alkali condition under high temperature reduced its molecular weight.
Longer treatment time further decreased the molecular weight of chitosan and hence its viscosity.
Electrospinning of PCL/chitosan blend was possible at higher chitosan ratio, and SEM images showed a decrease in fiber diameter and narrower distribution with increase in the chitosan ratio.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Roozbahani, Fatemeh& Sultana, Naznin& Fauzi Ismail, Ahmad& Nouparvar, Hamed. 2013. Effects of Chitosan Alkali Pretreatment on the Preparation of Electrospun PCLChitosan Blend Nanofibrous Scaffolds for Tissue Engineering Application. Journal of Nanomaterials،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1031497
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Roozbahani, Fatemeh…[et al.]. Effects of Chitosan Alkali Pretreatment on the Preparation of Electrospun PCLChitosan Blend Nanofibrous Scaffolds for Tissue Engineering Application. Journal of Nanomaterials No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1031497
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Roozbahani, Fatemeh& Sultana, Naznin& Fauzi Ismail, Ahmad& Nouparvar, Hamed. Effects of Chitosan Alkali Pretreatment on the Preparation of Electrospun PCLChitosan Blend Nanofibrous Scaffolds for Tissue Engineering Application. Journal of Nanomaterials. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1031497
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1031497
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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