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Reducing Agents Decrease the Oxidative Burst and Improve Clinical Outcomes in COPD Patients: A Randomised Controlled Trial on the Effects of Sulphurous Thermal Water Inhalation
المؤلفون المشاركون
Contoli, Marco
Gnesini, Giulia
Forini, Giacomo
Marku, Brunilda
Pauletti, Alessia
Padovani, Anna
Casolari, Paolo
Taurino, Liliana
Ferraro, Andrea
Chicca, Milva
Ciaccia, Adalberto
Pinamonti, Silvano
Papi, Alberto
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-23
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Background.
Inhalation of thermal water with antioxidant properties is empirically used for COPD.
Aims.
To evaluate the effects of sulphurous thermal water (reducing agents) on airway oxidant stress and clinical outcomes in COPD.
Methods.
Forty moderate-to-severe COPD patients were randomly assigned to receive 12-day inhalation with sulphurous thermal water or isotonic saline.
Patients were assessed for superoxide anion (O2-) production in the exhaled breath condensate and clinical outcomes at recruitment, the day after the conclusion of the 12-day inhalation treatment, and one month after the end of the inhalation treatment.
Results.
Inhalation of reducing agents resulted in a significant reduction of O2- production in exhaled breath condensate of COPD patients at the end of the inhalatory treatment and at followup compared to baseline.
A significant improvement in the COPD assessment test (CAT) questionnaire was shown one month after the end of the inhalatory treatment only in patients receiving sulphurous water.
Conclusion.
Thermal water inhalation produced an in vivo antioxidant effect and improvement in health status in COPD patients.
Larger studies are required in order to evaluate whether inhalation of thermal water is able to modify relevant clinical outcomes of the disease (the study was registered at clinicaltrial.gov—identifier: NCT01664767).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Contoli, Marco& Gnesini, Giulia& Forini, Giacomo& Marku, Brunilda& Pauletti, Alessia& Padovani, Anna…[et al.]. 2013. Reducing Agents Decrease the Oxidative Burst and Improve Clinical Outcomes in COPD Patients: A Randomised Controlled Trial on the Effects of Sulphurous Thermal Water Inhalation. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1033444
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Contoli, Marco…[et al.]. Reducing Agents Decrease the Oxidative Burst and Improve Clinical Outcomes in COPD Patients: A Randomised Controlled Trial on the Effects of Sulphurous Thermal Water Inhalation. The Scientific World Journal No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1033444
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Contoli, Marco& Gnesini, Giulia& Forini, Giacomo& Marku, Brunilda& Pauletti, Alessia& Padovani, Anna…[et al.]. Reducing Agents Decrease the Oxidative Burst and Improve Clinical Outcomes in COPD Patients: A Randomised Controlled Trial on the Effects of Sulphurous Thermal Water Inhalation. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1033444
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1033444
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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