Crystal Structure of a Conserved Hypothetical Protein MJ0927 from Methanocaldococcus jannaschii Reveals a Novel Quaternary Assembly in the Nif3 Family
المؤلفون المشاركون
Chen, Sheng-Chia
Huang, Chi-Hung
Yang, Chia Shin
Kuan, Shu-Min
Chou, Shan-Ho
Chen, Yeh
Lin, Ching-Ting
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-28
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
A Nif3 family protein of Methanocaldococcus jannaschii, MJ0927, is highly conserved from bacteria to humans.
Although several structures of bacterial Nif3 proteins are known, no structure representing archaeal Nif3 has yet been reported.
The crystal structure of Methanocaldococcus jannaschii MJ0927 was determined at 2.47 Å resolution to understand the structural differences between the bacterial and archaeal Nif3 proteins.
Intriguingly, MJ0927 is found to adopt an unusual assembly comprising a trimer of dimers that forms a cage-like architecture.
Electrophoretic mobility-shift assays indicate that MJ0927 binds to both single-stranded and double-stranded DNA.
Structural analysis of MJ0927 reveals a positively charged region that can potentially explain its DNA-binding capability.
Taken together, these data suggest that MJ0927 adopts a novel quartenary architecture that could play various DNA-binding roles in Methanocaldococcus jannaschii.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Sheng-Chia& Huang, Chi-Hung& Yang, Chia Shin& Kuan, Shu-Min& Lin, Ching-Ting& Chou, Shan-Ho…[et al.]. 2014. Crystal Structure of a Conserved Hypothetical Protein MJ0927 from Methanocaldococcus jannaschii Reveals a Novel Quaternary Assembly in the Nif3 Family. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1034392
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Sheng-Chia…[et al.]. Crystal Structure of a Conserved Hypothetical Protein MJ0927 from Methanocaldococcus jannaschii Reveals a Novel Quaternary Assembly in the Nif3 Family. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1034392
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Sheng-Chia& Huang, Chi-Hung& Yang, Chia Shin& Kuan, Shu-Min& Lin, Ching-Ting& Chou, Shan-Ho…[et al.]. Crystal Structure of a Conserved Hypothetical Protein MJ0927 from Methanocaldococcus jannaschii Reveals a Novel Quaternary Assembly in the Nif3 Family. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1034392
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1034392
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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