Emerging Anticancer Potentials of Goniothalamin and Its Molecular Mechanisms
المؤلفون المشاركون
Jantan, Ibrahim
Seyed, Mohamed Ali
Bukhari, Syed Nasir Abbas
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-27
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The treatment of most cancers is still inadequate, despite tremendous steady progress in drug discovery and effective prevention.
Nature is an attractive source of new therapeutics.
Several medicinal plants and their biomarkers have been widely used for the treatment of cancer with less known scientific basis of their functioning.
Although a wide array of plant derived active metabolites play a role in the prevention and treatment of cancer, more extensive scientific evaluation of their mechanisms is still required.
Styryl-lactones are a group of secondary metabolites ubiquitous in the genus Goniothalamus that have demonstrated to possess antiproliferative activity against cancer cells.
A large body of evidence suggests that this activity is associated with the induction of apoptosis in target cells.
In an effort to promote further research on the genus Goniothalamus, this review offers a broad analysis of the current knowledge on Goniothalamin (GTN) or 5, 6, dihydro-6-styryl-2-pyronone (C13H12O2), a natural occurring styryl-lactone.
Therefore, it includes (i) the source of GTN and other metabolites; (ii) isolation, purification, and (iii) the molecular mechanisms of actions of GTN, especially the anticancer properties, and summarizes the role of GTN which is crucial for drug design, development, and application in future for well-being of humans.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Seyed, Mohamed Ali& Jantan, Ibrahim& Bukhari, Syed Nasir Abbas. 2014. Emerging Anticancer Potentials of Goniothalamin and Its Molecular Mechanisms. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1034493
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Seyed, Mohamed Ali…[et al.]. Emerging Anticancer Potentials of Goniothalamin and Its Molecular Mechanisms. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1034493
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Seyed, Mohamed Ali& Jantan, Ibrahim& Bukhari, Syed Nasir Abbas. Emerging Anticancer Potentials of Goniothalamin and Its Molecular Mechanisms. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1034493
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1034493
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر