Assessment of Tumor Cells in a Mouse Model of Diffuse Infiltrative Glioma by Raman Spectroscopy
المؤلفون المشاركون
Ohka, Fumiharu
Wakabayashi, Toshihiko
Tanahashi, Kuniaki
Momota, Hiroyuki
Kato, Akira
Motomura, Kazuya
Watabe, Naoki
Muraishi, Shuichi
Nakahara, Hitoshi
Saito, Yahachi
Takeuchi, Ichiro
Natsume, Atsushi
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-27
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Glioma of infiltrative nature is challenging for surgeons to achieve tumor-specific and maximal resection.
Raman spectroscopy provides structural information on the targeted materials as vibrational shifts.
We utilized Raman spectroscopy to distinguish invasive tumors from normal tissues.
Spectra obtained from replication-competent avian sarcoma-(RCAS-) based infiltrative glioma cells and glioma tissues (resembling low-grade human glioma) were compared with those obtained from normal mouse astrocytes and normal tissues.
In cell analysis, the spectra at 950–1000, 1030, 1050–1100, 1120–1130, 1120–1200, 1200–1300, 1300–1350, and 1450 cm−1 were significantly higher in infiltrative glioma cells than in normal astrocytes.
In brain tissue analysis, the spectra at 1030, 1050–1100, and 1200–1300 cm−1 were significantly higher in infiltrative glioma tissues than in normal brain tissues.
These spectra reflect the structures of proteins, lipids, and DNA content.
The sensitivity and specificity to predict glioma cells by distinguishing normal cells were 98.3% and 75.0%, respectively.
Principal component analysis elucidated the significance of spectral difference between tumor tissues and normal tissues.
It is possible to distinguish invasive tumors from normal tissues by using Raman spectroscopy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tanahashi, Kuniaki& Natsume, Atsushi& Ohka, Fumiharu& Momota, Hiroyuki& Kato, Akira& Motomura, Kazuya…[et al.]. 2014. Assessment of Tumor Cells in a Mouse Model of Diffuse Infiltrative Glioma by Raman Spectroscopy. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1034585
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tanahashi, Kuniaki…[et al.]. Assessment of Tumor Cells in a Mouse Model of Diffuse Infiltrative Glioma by Raman Spectroscopy. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1034585
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tanahashi, Kuniaki& Natsume, Atsushi& Ohka, Fumiharu& Momota, Hiroyuki& Kato, Akira& Motomura, Kazuya…[et al.]. Assessment of Tumor Cells in a Mouse Model of Diffuse Infiltrative Glioma by Raman Spectroscopy. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1034585
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1034585
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر