Serum Prolidase Activity and Oxidative Stress in Diabetic Nephropathy and End Stage Renal Disease: A Correlative Study with Glucose and Creatinine
المؤلفون المشاركون
Verma, Akhilesh Kumar
Chandra, Subhash
Singh, Rana Gopal
Singh, Tej Bali
Srivastava, Ragini
Srivastava, Shalabh
المصدر
Biochemistry Research International
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-09-08
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Association of oxidative stress and serum prolidase activity (SPA) has been reported in many chronic diseases.
The study was aimed at evaluating the correlation of glucose and creatinine to SPA and oxidative stress in patients with diabetic nephropathy (DN) and end stage renal disease (ESRD) concerned with T2DM.
50 healthy volunteers, 50 patients with T2DM, 86 patients with DN, and 43 patients with ESRD were considered as control-1, control-2, case-1, and case-2, respectively.
Blood glucose, creatinine, SPA, total oxidant status (TOS), total antioxidant status (TAS), and oxidative stress index (OSI) were measured by colorimetric tests.
SPA, TOS, and OSI were significantly increased in case-1 and case-2 than control-1 and control-2, while TAS was significantly decreased (P<0.001).
Blood glucose was linearly correlated to SPA, TOS, TAS, and OSI in control-2, case-1 and case-2 (P<0.001).
Serum creatinine was linearly correlated with SPA, TOS, TAS and OSI in control-2 and case-1 (P<0.001).
In case-2, serum creatinine was significantly correlated with SPA only (P<0.001).
Thus, the study concluded that SPA and oxidative stress significantly correlated with blood glucose and creatinine.
SPA, TOS, TAS, and OSI can be used as biomarkers for diagnosis of kidney damage.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Verma, Akhilesh Kumar& Chandra, Subhash& Singh, Rana Gopal& Singh, Tej Bali& Srivastava, Shalabh& Srivastava, Ragini. 2014. Serum Prolidase Activity and Oxidative Stress in Diabetic Nephropathy and End Stage Renal Disease: A Correlative Study with Glucose and Creatinine. Biochemistry Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1034626
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Verma, Akhilesh Kumar…[et al.]. Serum Prolidase Activity and Oxidative Stress in Diabetic Nephropathy and End Stage Renal Disease: A Correlative Study with Glucose and Creatinine. Biochemistry Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1034626
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Verma, Akhilesh Kumar& Chandra, Subhash& Singh, Rana Gopal& Singh, Tej Bali& Srivastava, Shalabh& Srivastava, Ragini. Serum Prolidase Activity and Oxidative Stress in Diabetic Nephropathy and End Stage Renal Disease: A Correlative Study with Glucose and Creatinine. Biochemistry Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1034626
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1034626
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر