Anti-NMDA Receptor Encephalitis Presenting as an Acute Psychotic Episode in a Young Woman: An Underdiagnosed yet Treatable Disorder
المؤلفون المشاركون
Keller, Shikma
Roitman, Pablo
Bonne, Omer
Lotan, Amit
Ben-Hur, T.
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-10-07
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
علم النفس
الطب البشري
الطب النفسي
الملخص EN
Anti-NMDA receptor (NMDAR) encephalitis is a recently identified autoimmune disorder with prominent psychiatric symptoms.
Patients usually present with acute behavioral change, psychosis, catatonic symptoms, memory deficits, seizures, dyskinesias, and autonomic instability.
In female patients an ovarian teratoma is often identified.
We describe a 32-year-old woman who presented with acute psychosis.
Shortly after admission, she developed generalized seizures and deteriorated into a catatonic state.
Although ancillary tests including MRI, electroencephalogram, and cerebrospinal fluid (CSF) analysis were unremarkable, the presentation of acute psychosis in combination with recurrent seizures and a relentless course suggested autoimmune encephalitis.
The patient underwent pelvic ultrasound which disclosed a dermoid cyst and which led to an urgent cystectomy.
Plasmapheresis was then initiated, yielding partial response over the next two weeks.
Following the detection of high titers of anti-NMDAR antibodies in the CSF, the patient ultimately received second line immunosuppressive treatment with rituximab.
Over several months of cognitive rehabilitation a profound improvement was eventually noted, although minor anterograde memory deficits remained.
In this report we call for attention to the inclusion of anti-NMDAR encephalitis in the differential diagnosis of acute psychosis.
Prompt diagnosis is critical as early immunotherapy and tumor removal could dramatically affect outcomes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Keller, Shikma& Roitman, Pablo& Ben-Hur, T.& Bonne, Omer& Lotan, Amit. 2014. Anti-NMDA Receptor Encephalitis Presenting as an Acute Psychotic Episode in a Young Woman: An Underdiagnosed yet Treatable Disorder. Case Reports in Psychiatry،Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-1034934
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Keller, Shikma…[et al.]. Anti-NMDA Receptor Encephalitis Presenting as an Acute Psychotic Episode in a Young Woman: An Underdiagnosed yet Treatable Disorder. Case Reports in Psychiatry No. 2014 (2014), pp.1-3.
https://search.emarefa.net/detail/BIM-1034934
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Keller, Shikma& Roitman, Pablo& Ben-Hur, T.& Bonne, Omer& Lotan, Amit. Anti-NMDA Receptor Encephalitis Presenting as an Acute Psychotic Episode in a Young Woman: An Underdiagnosed yet Treatable Disorder. Case Reports in Psychiatry. 2014. Vol. 2014, no. 2014, pp.1-3.
https://search.emarefa.net/detail/BIM-1034934
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1034934
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر