Efficacy and Safety of Clearing Heat and Detoxifying Injection in the Treatment of Influenza: A Randomized, Double-Blinded, Placebo-Controlled Trial
المؤلفون المشاركون
Wei, Baolin
Liu, Xinqiao
Zhang, Yaqing
Huang, Xiaomin
Tan, Yuping
Sun, Zengtao
Yu, Liu
Yuhong, Huang
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-11-25
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objective.
To evaluate the efficacy and safety of CHDI in the treatment of influenza infection.
Method.
A randomized double-blind, double dummy trial was conducted.
Influenza patients with a positive influenza A rapid test diagnosis were randomized to receive CHDI or oseltamivir.
Primary outcome was assessed by the median fever alleviation time and clearance time, and secondary outcome was total scores of influenza symptoms.
Results.
One hundred thirty-nine participants were screened and 34 had a RT-PCR laboratory confirmation of influenza virus infection.
Fever alleviation time was 2.5 and 5 hours in CHDI and oseltamivir, respectively, and fever clearance time was 32.5 and 49 hours.
The HR of fever alleviation and clearance time shows no significant difference between two groups.
Total scores of influenza symptoms descended significantly in both groups after treatment and descended more in CHDI than oseltamivir on day 2.
Similar to total symptoms severity score, fever severity score descend more significantly in CHDI than oseltamivir on day 2, and there were no differences on other symptoms.
Conclusions.
CHDI have a similar effect to oseltamivir in reducing the duration of influenza illness.
CHDI was well tolerated, with no serious adverse events noted during the study period.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yu, Liu& Yuhong, Huang& Wei, Baolin& Liu, Xinqiao& Zhang, Yaqing& Huang, Xiaomin…[et al.]. 2014. Efficacy and Safety of Clearing Heat and Detoxifying Injection in the Treatment of Influenza: A Randomized, Double-Blinded, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1035107
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yu, Liu…[et al.]. Efficacy and Safety of Clearing Heat and Detoxifying Injection in the Treatment of Influenza: A Randomized, Double-Blinded, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1035107
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yu, Liu& Yuhong, Huang& Wei, Baolin& Liu, Xinqiao& Zhang, Yaqing& Huang, Xiaomin…[et al.]. Efficacy and Safety of Clearing Heat and Detoxifying Injection in the Treatment of Influenza: A Randomized, Double-Blinded, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1035107
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1035107
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر