Comparison of the Effects of Acarbose and TZQ-F, a New Kind of Traditional Chinese Medicine to Treat Diabetes, Chinese Healthy Volunteers
المؤلفون المشاركون
Baohe, Wang
Wenxu, Fu
Yanfen, Li
Ziqiang, Li
Liu, Yang
Shirong, Liu
Jinxia, Sun
Na, Li
Deqin, Zhang
Yu, Liu
Yuhong, Huang
Gao, Xiumei
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-06
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Ethnopharmacological Relevance.
TZQ-F has been traditionally used in Traditional Chinese Medicine as a formula for the treatment of diabetes.
Aim of the Study.
This study aims to compare the pharmacologic effects and gastrointestinal adverse events between TZQ-F and acarbose.
Methods.
The double-blind randomized placebo-controlled fivefold crossover study was performed in 20 healthy male volunteers.
Plasma glucose, plasma IRI, and plasma C-peptide were measured to assess the pharmacologic effects.
Flatus and bowel activity were measured to assess the adverse event of gastrointestinal effect.
Results.
3 and 4 tablets of TZQ decreased the Cmax of plasma glucose compared with that of the previous day and with placebo.
3 tablets also decreased Cmax of plasma C-peptide compared with placebo.
4 tablets increased Cmax of plasma insulin after breakfast and the AUC of plasma C-peptide after breakfast and dinner.
2 tablets did not decrease plasma glucose and elevated the Cmax and AUC of C-peptide after breakfast and dinner, respectively.
Acarbose 50 mg decreased the Cmax of plasma insulin and C-peptide after breakfast and the Cmax of plasma glucose and C-peptide after dinner.
The subjects who received TZQ did not report any abdominal adverse events.
Conclusions.
3 tablets of TZQ have the same effects as the acarbose.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yuhong, Huang& Wenxu, Fu& Yanfen, Li& Yu, Liu& Ziqiang, Li& Liu, Yang…[et al.]. 2014. Comparison of the Effects of Acarbose and TZQ-F, a New Kind of Traditional Chinese Medicine to Treat Diabetes, Chinese Healthy Volunteers. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1035150
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yuhong, Huang…[et al.]. Comparison of the Effects of Acarbose and TZQ-F, a New Kind of Traditional Chinese Medicine to Treat Diabetes, Chinese Healthy Volunteers. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1035150
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yuhong, Huang& Wenxu, Fu& Yanfen, Li& Yu, Liu& Ziqiang, Li& Liu, Yang…[et al.]. Comparison of the Effects of Acarbose and TZQ-F, a New Kind of Traditional Chinese Medicine to Treat Diabetes, Chinese Healthy Volunteers. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1035150
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1035150
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر