![](/images/graphics-bg.png)
Amides from Piper as a Diuretic: Behind the Ethnopharmacological Uses of Piper glabratum Kunth
المؤلفون المشاركون
Botelho Lourenço, Emerson Luiz
Lima Prando, Thiago Bruno
Gasparotto Junior, Arquimedes
Baciquete, Tatiane da Fonseca
Vieira, Jennifer Alexandra Castanho
Bressan, Jaqueline
Gasparotto, Francielly Mourão
Jesus, Douglas Rossi
Cardozo Junior, Euclides Lara
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-01
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Several species of the genus Piper are known in Brazilian folk medicine as having diuretic activity.
So, we propose to investigate the acute diuretic activity and the possible toxic effects of Piper glabratum Kunth, popularly known as false Jaborandi.
Additionally, we propose to check whether there is any correlation between the biological activities of the crude extract (MEPG) and its 2-methoxy-4,5-methylenedioxy-trans-cinnamoyl-pyrrolidine (MMCP) in Wistar rats.
The MEPG was fractioned by chromatography column and the MMCP was identified by analyses of 1H and 13C RMN spectral data and correlations.
Both MEPG and MMCP were assayed for diuretic activity.
The preparations obtained were orally administered in a single dose to rats.
The urine excretion, pH, density, conductivity, and content of Na+, K+, Cl−, and HCO 3 - were measured in the urine of saline-loaded animals.
Additionally, acute toxicity of the extract was also evaluated.
MMCP at doses of 30 mg/kg was able to increase the urine volume, pH, and HCO 3 - excretion.
Moreover, high dosage of MEPG showed important liver toxicity and elevated mortality when injected intraperitoneally.
The results indicate that the MMCP shows important diuretic properties when administered in Wistar rats.
Additionally, MEPG can induce important acute toxicity if given in high doses.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lima Prando, Thiago Bruno& Baciquete, Tatiane da Fonseca& Vieira, Jennifer Alexandra Castanho& Bressan, Jaqueline& Gasparotto, Francielly Mourão& Jesus, Douglas Rossi…[et al.]. 2014. Amides from Piper as a Diuretic: Behind the Ethnopharmacological Uses of Piper glabratum Kunth. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1035303
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lima Prando, Thiago Bruno…[et al.]. Amides from Piper as a Diuretic: Behind the Ethnopharmacological Uses of Piper glabratum Kunth. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1035303
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lima Prando, Thiago Bruno& Baciquete, Tatiane da Fonseca& Vieira, Jennifer Alexandra Castanho& Bressan, Jaqueline& Gasparotto, Francielly Mourão& Jesus, Douglas Rossi…[et al.]. Amides from Piper as a Diuretic: Behind the Ethnopharmacological Uses of Piper glabratum Kunth. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1035303
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1035303
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)