Effect of Integrated Cognitive Therapy on Hippocampal Functional Connectivity Patterns in Stroke Patients with Cognitive Dysfunction: A Resting-State fMRI Study
المؤلفون المشاركون
Yang, Shanli
Jiang, Cai
Ye, Haicheng
Tao, Jing
Huang, Jia
Gao, Yanling
Lin, Zhicheng
Chen, Lidian
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-12-08
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
This study aimed to identify abnormal hippocampal functional connectivity (FC) following ischemic stroke using resting-state fMRI.
We also explored whether abnormal hippocampal FC could be modulated by integrated cognitive therapy and tested whether these alterations were associated with cognitive performance.
Methods.
18 right-handed cognitively impaired ischemic stroke patients and 18 healty control (HC) subjects were included in this study.
Stroke subjects were scanned at baseline and after integrated cognitive therapy, while HCs were only scanned at baseline, to identify regions that show significant correlations with the seed region.
Behavioral and cognitive assessments were obtained before each scan.
Results.
During the resting state, we found abnormal hippocampal FC associated with temporal regions, insular cortex, cerebellum, and prefrontal cortex in stroke patients compared to HCs.
After integrated cognitive therapy, however, the stroke group showed increased hippocampal FC mainly located in the prefrontal gyrus and the default mode network (DMN).
Altered hippocampal FC was associated with cognitive improvement.
Conclusion.
Resting-state fMRI may provide novel insight into the study of functional networks in the brain after stroke.
Furthermore, altered hippocampal FC may be a compensatory mechanism for cognitive recovery after ischemic stroke.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Shanli& Jiang, Cai& Ye, Haicheng& Tao, Jing& Huang, Jia& Gao, Yanling…[et al.]. 2014. Effect of Integrated Cognitive Therapy on Hippocampal Functional Connectivity Patterns in Stroke Patients with Cognitive Dysfunction: A Resting-State fMRI Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1035495
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Shanli…[et al.]. Effect of Integrated Cognitive Therapy on Hippocampal Functional Connectivity Patterns in Stroke Patients with Cognitive Dysfunction: A Resting-State fMRI Study. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1035495
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Shanli& Jiang, Cai& Ye, Haicheng& Tao, Jing& Huang, Jia& Gao, Yanling…[et al.]. Effect of Integrated Cognitive Therapy on Hippocampal Functional Connectivity Patterns in Stroke Patients with Cognitive Dysfunction: A Resting-State fMRI Study. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1035495
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1035495
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر