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Assessment of Gastric Phenotypes Using Magnifying Narrow-Band Imaging for Differentiation of Gastric Carcinomas from Adenomas
المؤلفون المشاركون
Kobayashi, Masaaki
Hashimoto, Satoru
Nishikura, Ken
Mizuno, Ken-Ichi
Takeuchi, Manabu
Ajioka, Yoichi
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-10-13
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Conventional white-light endoscopy and forceps biopsy are insufficient for definitive diagnosis of gastric adenoma.
Immunohistochemical studies have reported an obvious phenotypic difference between adenomas and carcinomas.
We investigated the utility of narrow-band imaging with magnifying endoscopy (NBI-ME) for mucin phenotypic assessment to differentiate carcinomas from adenomas.
Methods.
NBI-ME findings were classified into A, B, and AB types, which revealed papillary, tubular pits and groove microstructures, respectively.
To investigate A-B classifications retrospectively, 137 patients (155 lesions) that were diagnosed pretherapeutically with adenoma or borderline lesions by biopsy were enrolled.
The mucin phenotype was analyzed immunohistochemically in the first 60 lesions.
Results.
After endoscopic submucosal dissection, A type and AB type lesions were determined histologically as carcinoma (81/82, 99%).
B type lesions were adenoma (29/73, 40%) and carcinoma (44/73, 60%).
A or AB type correlated to histological carcinomas (sensitivity 65%, specificity 97%, and accuracy 71%).
Mucin phenotypes were gastric or gastrointestinal in A type and AB type carcinomas (31/37, 84%) and intestinal in B type adenomas and carcinomas (21/23, 91%).
Conclusions.
NBI-ME has the advantage of the assessment of mucin phenotypes in gastric carcinomas and adenomas.
The proposed A-B classification is useful, especially for differentiation of gastric or gastrointestinal carcinomas from adenomas.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kobayashi, Masaaki& Hashimoto, Satoru& Nishikura, Ken& Mizuno, Ken-Ichi& Takeuchi, Manabu& Ajioka, Yoichi. 2014. Assessment of Gastric Phenotypes Using Magnifying Narrow-Band Imaging for Differentiation of Gastric Carcinomas from Adenomas. Gastroenterology Research and Practice،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1035879
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kobayashi, Masaaki…[et al.]. Assessment of Gastric Phenotypes Using Magnifying Narrow-Band Imaging for Differentiation of Gastric Carcinomas from Adenomas. Gastroenterology Research and Practice No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1035879
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kobayashi, Masaaki& Hashimoto, Satoru& Nishikura, Ken& Mizuno, Ken-Ichi& Takeuchi, Manabu& Ajioka, Yoichi. Assessment of Gastric Phenotypes Using Magnifying Narrow-Band Imaging for Differentiation of Gastric Carcinomas from Adenomas. Gastroenterology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1035879
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1035879
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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