Breast Cancer with Neoductgenesis: Histopathological Criteria and Its Correlation with Mammographic and Tumour Features
المؤلفون المشاركون
Fjallskog, Marie-Louise
Pinder, Sarah E.
Sollie, Thomas
Christensson, Gunilla
Abdsaleh, Shahin
Tot, Tibor
Wärnberg, Fredrik
Blomqvist, Carl
Amini, Rose-Marie
Zhou, Wenjing
المصدر
International Journal of Breast Cancer
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-10-07
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Introduction.
Breast cancer with mammographic casting type calcifications, high grade DCIS with an abnormal number of ducts, periductal desmoplastic reaction, lymphocyte infiltration, and tenascin-C (TN-C) overexpression has been proposed to represent a more aggressive form of breast cancer and has been denominated as breast cancer with neoductgenesis.
We developed histopathological criteria for neoductgenesis in order to study reproducibility and correlation with other tumour markers.
Methods.
74 cases of grades 2 and 3 DCIS, with or without an invasive component, were selected.
A combined score of the degree(s) of concentration of ducts, lymphocyte infiltration, and periductal fibrosis was used to classify cases as showing neoductgenesis, or not.
Diagnostic reproducibility, correlation with tumour markers, and mammographic features were studied.
Results.
Twenty-three of 74 cases were diagnosed with neoductgenesis.
The kappa value between pathologists showed moderate reproducibility (0.50) (95% CI; 0.41–0.60).
Neoductgenesis correlated significantly with malignant type microcalcifications and TN-C expression ( P = 0.008 and 0.04) and with ER, PR, and HER2 status ( P < 0.00001 for all three markers).
Conclusions.
We developed histological criteria for breast cancer with neoductgenesis.
Neoductgenesis, by our applied histopathological definition was related to more aggressive tumour biology and malignant mammographic calcifications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhou, Wenjing& Sollie, Thomas& Tot, Tibor& Pinder, Sarah E.& Amini, Rose-Marie& Blomqvist, Carl…[et al.]. 2014. Breast Cancer with Neoductgenesis: Histopathological Criteria and Its Correlation with Mammographic and Tumour Features. International Journal of Breast Cancer،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1036306
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhou, Wenjing…[et al.]. Breast Cancer with Neoductgenesis: Histopathological Criteria and Its Correlation with Mammographic and Tumour Features. International Journal of Breast Cancer No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1036306
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhou, Wenjing& Sollie, Thomas& Tot, Tibor& Pinder, Sarah E.& Amini, Rose-Marie& Blomqvist, Carl…[et al.]. Breast Cancer with Neoductgenesis: Histopathological Criteria and Its Correlation with Mammographic and Tumour Features. International Journal of Breast Cancer. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1036306
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1036306
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر