Increased Incidence of Thyroid Dysfunction and Autoimmunity in Patients with Vernal Keratoconjunctivitis
المؤلفون المشاركون
Stagi, Stefano
de Martino, Maurizio
Pucci, Neri
Di Grande, Laura
de Libero, Cinzia
Caputo, Roberto
Pantano, Stefano
Mattei, Ivan
Mori, Francesca
Novembre, Elio
المصدر
International Journal of Endocrinology
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-20
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Hormones may play a role in the pathophysiology of vernal keratoconjunctivitis (VKC).
An increased incidence of thyroid autoantibodies was recently observed in VKC, although there were no data on thyroid function.
Two hundred and eighty-eight patients (202 males, 86 females; range 5.5 to 16.9 years) with VKC were evaluated and compared with 188 normal age- and sex-matched subjects.
In all subjects, serum concentrations of free T4, TSH, thyroperoxidase, thyroglobulin, and TSHr autoantibodies were evaluated.
In VKC, the family history of thyroid diseases showed no significant differences compared to the controls (9.4 versus 8.6%), whereas the family history of autoimmune diseases was significantly higher (13.2% versus 6.3%; P < 0.05 ).
Subclinical hypothyroidism was diagnosed in 6.6% (versus 1.6% of the controls; P < 0.05 ) and overt hypothyroidism in 0.7% (versus 0.0% of the controls; P = N S ).
Finally, 5.2% of patients were positive for thyroid autoantibodies, which were significantly higher with respect to the controls (0.5%, P < 0.05 ).
In the patients positive for thyroid autoantibodies, 80% showed a sonography pattern that suggested autoimmune thyroiditis.
Thyroid function and autoimmunity abnormalities are frequently present in children with VKC.
Children with VKC should be screened for thyroid function and evaluated for thyroid autoimmunity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Stagi, Stefano& Pucci, Neri& Di Grande, Laura& de Libero, Cinzia& Caputo, Roberto& Pantano, Stefano…[et al.]. 2014. Increased Incidence of Thyroid Dysfunction and Autoimmunity in Patients with Vernal Keratoconjunctivitis. International Journal of Endocrinology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1036593
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Stagi, Stefano…[et al.]. Increased Incidence of Thyroid Dysfunction and Autoimmunity in Patients with Vernal Keratoconjunctivitis. International Journal of Endocrinology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1036593
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Stagi, Stefano& Pucci, Neri& Di Grande, Laura& de Libero, Cinzia& Caputo, Roberto& Pantano, Stefano…[et al.]. Increased Incidence of Thyroid Dysfunction and Autoimmunity in Patients with Vernal Keratoconjunctivitis. International Journal of Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1036593
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1036593
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر