Photoprotective Effect of the Plant Collaea argentina against Adverse Effects Induced by Photodynamic Therapy
المؤلفون المشاركون
Mamone, Leandro
Sáenz, Daniel
Vallecorsa, Pablo
Batlle, Alcira
Casas, Adriana
Di Venosa, Gabriela
المصدر
International Journal of Photoenergy
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-27
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Photodynamic therapy (PDT) is a treatment modality for tumours and other accessible lesions based on the combination of light and a photosensitizer (PS) accumulated in the target tissue.
The main disadvantage of PDT is PS retention after treatment during long time periods that conduces to cutaneous damage.
It is believed that singlet oxygen is responsible for that skin photosensitization.
The aim of this work was to evaluate the photoprotective activity of the methanolic extract of the Argentinian plant Collaea argentina against PDT under several treatments and employing different PSs.
C.
argentina exhibited photoprotective activity against aminolevulinic acid- (ALA-) PDT in the LM2 murine adenocarcinoma cell line.
The photoprotection was dependant on the extract concentration and the incubation time, being detectable from 40 μg/mL onwards and at least after 3 h exposure of the cells.
C.
argentina extract protects these mammalian tumor cells against PDT effects, and it interferes with the oxygen singlet production from PSs during PDT treatment.
We propose that it will be a promising agent to protect cells against PDT-induced skin sensitivity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mamone, Leandro& Sáenz, Daniel& Vallecorsa, Pablo& Batlle, Alcira& Casas, Adriana& Di Venosa, Gabriela. 2014. Photoprotective Effect of the Plant Collaea argentina against Adverse Effects Induced by Photodynamic Therapy. International Journal of Photoenergy،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1036927
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mamone, Leandro…[et al.]. Photoprotective Effect of the Plant Collaea argentina against Adverse Effects Induced by Photodynamic Therapy. International Journal of Photoenergy No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1036927
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mamone, Leandro& Sáenz, Daniel& Vallecorsa, Pablo& Batlle, Alcira& Casas, Adriana& Di Venosa, Gabriela. Photoprotective Effect of the Plant Collaea argentina against Adverse Effects Induced by Photodynamic Therapy. International Journal of Photoenergy. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1036927
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1036927
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر