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Extraction and Bioactivity Analysis of Major Flavones Compounds from Scutellaria baicalensis Using In Vitro Assay and Online Screening HPLC-ABTS System
المؤلفون المشاركون
Ma, Jin Yeul
Lee, Kwang Jin
Oh, You-Chang
Song, Na-Young
Jung, Pil Mun
Kim, Taesoo
المصدر
Journal of Analytical Methods in Chemistry
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-31
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The extraction efficiency of a number of solvent compositions for the improvement of bioactive compounds yield from S.
baicalensis has been investigated.
Also, free radical scavengers in the glycoside baicalin (BG), wogonoside (WG), aglycon baicalein (B), and wogonin (W) compounds of S.
baicalensis were screened, identified, and quantified using coupled offline ABTS and online screening HPLC-ABTS assay.
Increasing ethanol content fractions resulted in decreased extract yield of bioactive compounds.
In this case, the best yield of 37.01 mg/g in BG, WG, B, and W compounds was obtained by a dipping method with an extraction time of 4 h.
In addition, the yield (43.05%) and IC50 (34.04 μg/mL) determined through ABTS assay of the 60% aqueous ethanol extract were the most satisfactory of all solvent solutions tested.
This result shows that an online screening HPLC-ABTS assay can be a powerful technique for the rapid characterization of bioactivity compounds in plant extracts.
Moreover, their anti-inflammatory activities were evaluated via analyzed inhibitory effect on NO and inflammatory cytokine production.
Furthermore, WG and W exhibited the strong inhibitory effects on inflammatory mediator production including NO, IL-6, and IL-1β in LPS-stimulated RAW 264.7 macrophages.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lee, Kwang Jin& Jung, Pil Mun& Oh, You-Chang& Song, Na-Young& Kim, Taesoo& Ma, Jin Yeul. 2014. Extraction and Bioactivity Analysis of Major Flavones Compounds from Scutellaria baicalensis Using In Vitro Assay and Online Screening HPLC-ABTS System. Journal of Analytical Methods in Chemistry،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1039832
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lee, Kwang Jin…[et al.]. Extraction and Bioactivity Analysis of Major Flavones Compounds from Scutellaria baicalensis Using In Vitro Assay and Online Screening HPLC-ABTS System. Journal of Analytical Methods in Chemistry No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1039832
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lee, Kwang Jin& Jung, Pil Mun& Oh, You-Chang& Song, Na-Young& Kim, Taesoo& Ma, Jin Yeul. Extraction and Bioactivity Analysis of Major Flavones Compounds from Scutellaria baicalensis Using In Vitro Assay and Online Screening HPLC-ABTS System. Journal of Analytical Methods in Chemistry. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1039832
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1039832
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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