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Study of Postprandial Lipaemia in Type 2 Diabetes Mellitus: Exenatide versus Liraglutide
المؤلفون المشاركون
Voukali, Maria
Kastrinelli, Irene
Stragalinou, Sapfo
Tasiopoulou, Dimitra
Paraskevopoulou, Pinelopi
Katsilambros, Nicholas
Ioannidis, Ioannis
Tentolouris, Nicholas
Kokkinos, Alexander
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-04
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Therapeutic approaches based on the actions of the incretin hormone GLP-1 have been widely established in the management of T2DM.
Nevertheless, much less research has been aimed at elucidating the role of GLP-1 in lipid metabolism and in particular postprandial dyslipidemia.
Exenatide and liraglutide are two GLP-1 receptor agonists which are currently available as subcutaneously administered treatment for T2DM but their chronic effects on postprandial lipaemia have not been well investigated.
The aim of this study is to examine the effect of treatment with either liraglutide or exenatide for two weeks on postprandial lipaemia in obese subjects with T2DM.
This study was a single-center, two-armed, randomized, controlled 2-week prospective intervention trial in 20 subjects with T2DM.
Patients were randomized to receive either liraglutide or exenatide treatment and underwent a standardized meal tolerance test early in the morning after 10 h fast at baseline (visit 1, beginning of treatment) and after a two-week treatment period (visit 2).
Exenatide and liraglutide both appear to be equally effective in lowering postprandial lipaemia after the first administration and after a two-week treatment.
The mechanisms which lead to this phenomenon, which seem to be independent of gastric emptying, are yet to be studied.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Voukali, Maria& Kastrinelli, Irene& Stragalinou, Sapfo& Tasiopoulou, Dimitra& Paraskevopoulou, Pinelopi& Katsilambros, Nicholas…[et al.]. 2014. Study of Postprandial Lipaemia in Type 2 Diabetes Mellitus: Exenatide versus Liraglutide. Journal of Diabetes Research،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1040284
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Voukali, Maria…[et al.]. Study of Postprandial Lipaemia in Type 2 Diabetes Mellitus: Exenatide versus Liraglutide. Journal of Diabetes Research No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1040284
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Voukali, Maria& Kastrinelli, Irene& Stragalinou, Sapfo& Tasiopoulou, Dimitra& Paraskevopoulou, Pinelopi& Katsilambros, Nicholas…[et al.]. Study of Postprandial Lipaemia in Type 2 Diabetes Mellitus: Exenatide versus Liraglutide. Journal of Diabetes Research. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1040284
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1040284
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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