![](/images/graphics-bg.png)
Acarbose Treatment and the Risk of Cardiovascular Disease in Type 2 Diabetic Patients: A Nationwide Seven-Year Follow-Up Study
المؤلفون المشاركون
Chen, Jui-Ming
Chang, Cheng-Wei
Lin, Ying-Chieh
Sheu, Wayne Huey-Herng
Horng, Jorng-Tzong
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-07
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
To investigate the potential benefits of acarbose treatment on cardiovascular disease (CVD) in patients with type 2 diabetes by using nationwide insurance claim dataset.
Research Design and Methods.
Among 644,792 newly diagnosed type 2 diabetic patients without preexisting CVD in a nationwide cohort study, 109,139 (16.9%) who had received acarbose treatment were analyzed for CVD risk.
Those with CVD followed by acarbose therapy were also subjected to analysis.
Result.
During 7 years of follow-up, 5,081 patients (4.7%) developed CVD.
The crude hazard ratio (HR) and adjusted HR were 0.66 and 0.99, respectively.
The adjusted HR of CVD was 1.19, 0.70, and 0.38 when the duration of acarbose use was <12 months, 12–24 months, and >24 months, respectively.
Adjusted HR was 1.14, 0.64, and 0.41 with acarbose cumulative doses <54,750 mg, 54,751 to 109,500 mg, and >109,500 mg, respectively.
Conclusion.
In patients with type 2 diabetes without preexisting CVD, treatment with acarbose showed a transient increase in incidence of CVD in the initial 12 months followed by significant reductions of CVD in prolonged acarbose users.
After the first CVD events, continuous use of acarbose revealed neutral effect within the first 12 months.
The underlying mechanisms require further investigations.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Jui-Ming& Chang, Cheng-Wei& Lin, Ying-Chieh& Horng, Jorng-Tzong& Sheu, Wayne Huey-Herng. 2014. Acarbose Treatment and the Risk of Cardiovascular Disease in Type 2 Diabetic Patients: A Nationwide Seven-Year Follow-Up Study. Journal of Diabetes Research،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1040379
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Jui-Ming…[et al.]. Acarbose Treatment and the Risk of Cardiovascular Disease in Type 2 Diabetic Patients: A Nationwide Seven-Year Follow-Up Study. Journal of Diabetes Research No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1040379
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Jui-Ming& Chang, Cheng-Wei& Lin, Ying-Chieh& Horng, Jorng-Tzong& Sheu, Wayne Huey-Herng. Acarbose Treatment and the Risk of Cardiovascular Disease in Type 2 Diabetic Patients: A Nationwide Seven-Year Follow-Up Study. Journal of Diabetes Research. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1040379
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1040379
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)