Roles of the Chemokine System in Development of Obesity, Insulin Resistance, and Cardiovascular Disease

المؤلفون المشاركون

Yao, Longbiao
Herlea-Pana, Oana
Heuser-Baker, Janet
Chen, Yitong
Barlic-Dicen, Jana

المصدر

Journal of Immunology Research

العدد

المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-11، 11ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2014-03-15

دولة النشر

مصر

عدد الصفحات

11

التخصصات الرئيسية

الأحياء

الملخص EN

The escalating epidemic of obesity has increased the incidence of obesity-induced complications to historically high levels.

Adipose tissue is a dynamic energy depot, which stores energy and mobilizes it during nutrient deficiency.

Excess nutrient intake resulting in adipose tissue expansion triggers lipid release and aberrant adipokine, cytokine and chemokine production, and signaling that ultimately lead to adipose tissue inflammation, a hallmark of obesity.

This low-grade chronic inflammation is thought to link obesity to insulin resistance and the associated comorbidities of metabolic syndrome such as dyslipidemia and hypertension, which increase risk of type 2 diabetes and cardiovascular disease.

In this review, we focus on and discuss members of the chemokine system for which there is clear evidence of participation in the development of obesity and obesity-induced pathologies.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Yao, Longbiao& Herlea-Pana, Oana& Heuser-Baker, Janet& Chen, Yitong& Barlic-Dicen, Jana. 2014. Roles of the Chemokine System in Development of Obesity, Insulin Resistance, and Cardiovascular Disease. Journal of Immunology Research،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1040784

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Yao, Longbiao…[et al.]. Roles of the Chemokine System in Development of Obesity, Insulin Resistance, and Cardiovascular Disease. Journal of Immunology Research No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1040784

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Yao, Longbiao& Herlea-Pana, Oana& Heuser-Baker, Janet& Chen, Yitong& Barlic-Dicen, Jana. Roles of the Chemokine System in Development of Obesity, Insulin Resistance, and Cardiovascular Disease. Journal of Immunology Research. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1040784

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1040784