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Roles of the Chemokine System in Development of Obesity, Insulin Resistance, and Cardiovascular Disease
Joint Authors
Yao, Longbiao
Herlea-Pana, Oana
Heuser-Baker, Janet
Chen, Yitong
Barlic-Dicen, Jana
Source
Journal of Immunology Research
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-15
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The escalating epidemic of obesity has increased the incidence of obesity-induced complications to historically high levels.
Adipose tissue is a dynamic energy depot, which stores energy and mobilizes it during nutrient deficiency.
Excess nutrient intake resulting in adipose tissue expansion triggers lipid release and aberrant adipokine, cytokine and chemokine production, and signaling that ultimately lead to adipose tissue inflammation, a hallmark of obesity.
This low-grade chronic inflammation is thought to link obesity to insulin resistance and the associated comorbidities of metabolic syndrome such as dyslipidemia and hypertension, which increase risk of type 2 diabetes and cardiovascular disease.
In this review, we focus on and discuss members of the chemokine system for which there is clear evidence of participation in the development of obesity and obesity-induced pathologies.
American Psychological Association (APA)
Yao, Longbiao& Herlea-Pana, Oana& Heuser-Baker, Janet& Chen, Yitong& Barlic-Dicen, Jana. 2014. Roles of the Chemokine System in Development of Obesity, Insulin Resistance, and Cardiovascular Disease. Journal of Immunology Research،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1040784
Modern Language Association (MLA)
Yao, Longbiao…[et al.]. Roles of the Chemokine System in Development of Obesity, Insulin Resistance, and Cardiovascular Disease. Journal of Immunology Research No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1040784
American Medical Association (AMA)
Yao, Longbiao& Herlea-Pana, Oana& Heuser-Baker, Janet& Chen, Yitong& Barlic-Dicen, Jana. Roles of the Chemokine System in Development of Obesity, Insulin Resistance, and Cardiovascular Disease. Journal of Immunology Research. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1040784
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1040784