Fabrication and In Vitro Evaluation of Nanosized HydroxyapatiteChitosan-Based Tissue Engineering Scaffolds
المؤلفون المشاركون
Sultana, Naznin
Khan, Tareef Hayat
Sun, Tao
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-27
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Composite scaffolds based on biodegradable natural polymer and osteoconductive hydroxyapatite (HA) nanoparticles can be promising for a variety of tissue engineering (TE) applications.
This study addressed the fabrication of three-dimensional (3D) porous composite scaffolds composed of HA and chitosan fabricated via thermally induced phase separation and freeze-drying technique.
The scaffolds produced were subsequently characterized in terms of microstructure, porosity, and mechanical property.
In vitro degradation and in vitro biological evaluation were also investigated.
The scaffolds were highly porous and had interconnected pore structures.
The pore sizes ranged from several microns to a few hundred microns.
The incorporated HA nanoparticles were well mixed and physically coexisted with chitosan in composite scaffold structures.
The addition of 10% (w/w) HA nanoparticles to chitosan enhanced the compressive mechanical properties of composite scaffold compared to pure chitosan scaffold.
In vitro degradation results in phosphate buffered saline (PBS) showed slower uptake properties of composite scaffolds.
Moreover, the scaffolds showed positive response to mouse fibroblast L929 cells attachment.
Overall, the findings suggest that HA/chitosan composite scaffolds could be suitable for TE applications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sun, Tao& Khan, Tareef Hayat& Sultana, Naznin. 2014. Fabrication and In Vitro Evaluation of Nanosized HydroxyapatiteChitosan-Based Tissue Engineering Scaffolds. Journal of Nanomaterials،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1041266
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sun, Tao…[et al.]. Fabrication and In Vitro Evaluation of Nanosized HydroxyapatiteChitosan-Based Tissue Engineering Scaffolds. Journal of Nanomaterials No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1041266
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sun, Tao& Khan, Tareef Hayat& Sultana, Naznin. Fabrication and In Vitro Evaluation of Nanosized HydroxyapatiteChitosan-Based Tissue Engineering Scaffolds. Journal of Nanomaterials. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1041266
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1041266
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر