A Comparative Study of Bioartificial Bone Tissue Poly-L-lactic AcidPolycaprolactone and PLLA Scaffolds Applied in Bone Regeneration
المؤلفون المشاركون
Weng, Weizong
Song, Shaojun
Cao, Liehu
Chen, Xiao
Cai, Yuanqi
Li, Haihang
Zhou, Qirong
Zhang, Jun
Su, Jiacan
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-12-31
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Bioartificial bone tissue engineering is an increasingly popular technique to repair bone defect caused by injury or disease.
This study aimed to investigate the feasibility of PLLA/PCL (poly-L-lactic acid/polycaprolactone) by a comparison study of PLLA/PCL and PLLA scaffolds applied in bone regeneration.
Thirty healthy mature New Zealand rabbits on which 15 mm distal ulna defect model had been established were selected and then were divided into three groups randomly: group A (repaired with PLLA scaffold), group B (repaired with PLLA/PCL scaffold), and group C (no scaffold) to evaluate the bone-remodeling ability of the implants.
Micro-CT examination revealed the prime bone regeneration ability of group B in three groups.
Bone mineral density of surgical site in group B was higher than group A but lower than group C.
Meanwhile, the bone regeneration in both groups A and B proceeded with signs of inflammation for the initial fast degradation of scaffolds.
As a whole, PLLA/PCL scaffolds in vivo initially degrade fast and were better suited to repair bone defect than PLLA in New Zealand rabbits.
Furthermore, for the low mineral density of new bone and rapid degradation of the scaffolds, more researches were necessary to optimize the composite for bone regeneration.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Weng, Weizong& Song, Shaojun& Cao, Liehu& Chen, Xiao& Cai, Yuanqi& Li, Haihang…[et al.]. 2014. A Comparative Study of Bioartificial Bone Tissue Poly-L-lactic AcidPolycaprolactone and PLLA Scaffolds Applied in Bone Regeneration. Journal of Nanomaterials،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1042056
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Weng, Weizong…[et al.]. A Comparative Study of Bioartificial Bone Tissue Poly-L-lactic AcidPolycaprolactone and PLLA Scaffolds Applied in Bone Regeneration. Journal of Nanomaterials No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1042056
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Weng, Weizong& Song, Shaojun& Cao, Liehu& Chen, Xiao& Cai, Yuanqi& Li, Haihang…[et al.]. A Comparative Study of Bioartificial Bone Tissue Poly-L-lactic AcidPolycaprolactone and PLLA Scaffolds Applied in Bone Regeneration. Journal of Nanomaterials. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1042056
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1042056
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر